Results 31 to 40 of about 753,787 (333)

Histone acetyltransferase 1 is a succinyltransferase for histones and non‐histones and promotes tumorigenesis

open access: yesEMBO reports, 2020
Lysine succinylation (Ksucc) is an evolutionarily conserved and widespread post-translational modification. Histone acetyltransferase 1 (HAT1) is a type B histone acetyltransferase, regulating the acetylation of both histone and non-histone proteins. However, the role of HAT1 in succinylation modulation remains unclear.
Guang Yang   +14 more
openaire   +3 more sources

Epigenetic Modifications to H3K9 in Renal Tubulointerstitial Cells after Unilateral Ureteric Obstruction and TGF-β1 Stimulation

open access: yesFrontiers in Pharmacology, 2017
Introduction: Epigenetic regulation of fibrogenesis through post-translational histone modifications (marks) may be a key determinant of progression in renal disease. In this study, we examined the distribution and acquisition of histone 3 Lysine 9 (H3K9)
Timothy D. Hewitson   +8 more
doaj   +1 more source

Quantifying nuclear wide chromatin compaction by phasor analysis of histone Förster resonance energy transfer (FRET) in frequency domain fluorescence lifetime imaging microscopy (FLIM) data. [PDF]

open access: yes, 2020
The nanometer spacing between nucleosomes throughout global chromatin organisation modulates local DNA template access, and through continuous dynamic rearrangements, regulates genome function [1].
Gratton, Enrico   +4 more
core   +3 more sources

Association of Histones With Coagulofibrinolytic Responses and Organ Dysfunction in Adult Post-cardiac Arrest Syndrome

open access: yesFrontiers in Cardiovascular Medicine, 2022
BackgroundPatients successfully resuscitated from cardiac arrest often develop organ dysfunction caused by systemic inflammation and increased coagulation, leading to disseminated intravascular coagulation (DIC).
Asumi Mizugaki   +4 more
doaj   +1 more source

Flavanols in the nuclei of the tea bush (Camellia sinensis) - broadening the perspectives to human health

open access: yesJournal of Applied Botany and Food Quality, 2013
Flavanols as a small subclass of the flavonoids stain selectively blue with the special reagent p-dimethylaminocinnamaldehyde (DMACA). Because of the prominent blue colour it is easy to recognize the flavanols histochemically in the vacuoles of expanding
Jürgen Polster   +4 more
doaj   +1 more source

Histones and histone modifications in protozoan parasites

open access: yesCellular Microbiology, 2006
Protozoan parasites are early branching eukaryotes causing significant morbidity and mortality in humans and livestock. Single-celled parasites have evolved complex life cycles, which may involve multiple host organisms, and strategies to evade host immune responses.
Sergio O. Angel   +2 more
openaire   +2 more sources

Peeling and Sliding in Nucleosome Repositioning

open access: yes, 2007
We investigate the mechanisms of histone sliding and detachment with a stochastic model that couples thermally-induced, passive histone sliding with active motor-driven histone unwrapping.
G. Längst   +3 more
core   +1 more source

BPA-Induced Deregulation of Epigenetic Patterns: Effects on Female Zebrafish Reproduction [PDF]

open access: yes, 2016
Bisphenol A (BPA) is one of the commonest Endocrine Disruptor Compounds worldwide. It interferes with vertebrate reproduction, possibly by inducing deregulation of epigenetic mechanisms.
Carnevali, Oliana   +6 more
core   +1 more source

New Insights in Transcriptional Regulation of the Ethylene Response in Arabidopsis

open access: yesFrontiers in Plant Science, 2019
As any living organisms, plants must respond to a wide variety of environmental stimuli. Plant hormones regulate almost all aspects of plant growth and development.
Likai Wang   +3 more
doaj   +1 more source

Epigenetic Regulation of Matrix Metalloproteinase-1 and -3 Expression in Mycobacterium tuberculosis Infection. [PDF]

open access: yes, 2017
In pulmonary tuberculosis (TB), the inflammatory immune response against Mycobacterium tuberculosis (Mtb) is associated with tissue destruction and cavitation, which drives disease transmission, chronic lung disease, and mortality.
Alland   +52 more
core   +2 more sources

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