BRPF1 in cancer epigenetics: a key regulator of histone acetylation and a promising therapeutic target. [PDF]
Alexandrova E +12 more
europepmc +1 more source
Insertion of short L1 sequences generates inter-strain histone acetylation differences in the mouse [PDF]
Beverly Ann G. Boyboy, Kenji Ichiyanagi
openalex +1 more source
Alterations in brain metabolites in rats with experimental periodontitis: A metabolomic approach
Abstract Background Periodontitis (PD) is a chronic inflammatory disease with systemic effects. Emerging evidence suggests a link between periodontal inflammation and neurological changes, but the biochemical mechanisms in key brain regions, such as the hippocampus and amygdala, remain unclear.
Ramona Ramalho de Souza Pereira +9 more
wiley +1 more source
A histone acetylation-based predictive model for immunotherapy response and combinatorial targeting in cervical cancer. [PDF]
Zhang X +6 more
europepmc +1 more source
Salt‐induced nutritional and metabolic shifts in halophytes: implications for food security
Abstract Plant species vary in their response to salinity: some crops show a degree of salt tolerance, while halophytes – whether wild or cultivated – are characterized by a high capacity to thrive under saline conditions. Halophytes are considered a source of valuable secondary metabolites with potential economic value, yet they might also produce ...
Giulia Atzori +9 more
wiley +1 more source
ABSTRACT Rosuvastatin (RVS) is an HMG‐CoA reductase inhibitor with lipid‐lowering properties. This study aims to investigate the role of RVS in plaque formation in atherosclerosis (AS) and its functional mechanism. ApoE−/− mice were fed a high‐fat diet to generate a mouse model of AS.
Xin Fu +5 more
wiley +1 more source
Restoring Histone Acetylation Accelerates Diabetic Wound Repair by Improving the Spatiotemporal Dynamics of Macrophages. [PDF]
Singh K +11 more
europepmc +1 more source
ABSTRACT Alveolar epithelial cell pyroptosis exacerbates inflammation and tissue damage by releasing inflammatory mediators, thereby promoting the development of acute lung injury (ALI). However, the fundamental mechanism underlying alveolar epithelial cell pyroptosis in ALI has not yet been elucidated. Lipopolysaccharide (LPS) was used to simulate ALI
Lei Wang +5 more
wiley +1 more source
ABSTRACT Hepatocellular carcinoma (HCC) is a heterogeneous malignancy characterized by high mortality rates. This article presents a discussion of the role of ZNF652 in HCC cell proliferation and apoptosis, thereby identifying a new target for HCC treatment. The expression levels of ZNF652, circRHOT1, and SLC38A6 in HCC and healthy cells were analyzed.
Kang Chen +7 more
wiley +1 more source
The effects of histone H4 tail acetylations on cation-induced chromatin folding and self-association
Abdollah Allahverdi +6 more
openalex +1 more source

