Results 281 to 290 of about 35,141 (364)

Induction of NKG2D Ligands on Solid Tumors Requires Tumor-Specific CD8⁺ T Cells and Histone Acetyltransferases. [PDF]

Cancer Immunol Res, 2017
Hu J, Bernatchez C, Zhang L, Xia X, Kleinerman ES, Hung MC, Hwu P, Li S.   +7 more
europepmc   +1 more source

Is Enhancer Function Driven by Protein–Protein Interactions? From Bacteria to Leukemia

BioEssays, Volume 47, Issue 6, June 2025.
Enhancers are key regulatory elements that are conceptually conserved from bacteria to humans. Enhancer dysregulation is common in cancers, including leukemia. We argue that highly specific protein–protein interactions, including transcription factors, mediate enhancer‐promoter proximity to allow enhancer‐bound factors to directly act on RNA polymerase
Nicholas T. Crump, Thomas A. Milne
wiley   +1 more source

Ordered recruitment of histone acetyltransferases and the TRAP/Mediator complex to thyroid hormone-responsive promoters in vivo

, 2002
Dipali Sharma, Joseph D. Fondell
openalex   +1 more source

Regulation of chromosome stability by the histone H2A variant Htz1, the Swr1 chromatin remodeling complex, and the histone acetyltransferase NuA4 [PDF]

, 2004
Nevan J. Krogan, Kristin Baetz, Michael‐Christopher Keogh, Nira Datta, Chika Sawa, Trevor C. Y. Kwok, Natalie J. Thompson, Michael Davey, Jeff Pootoolal, Timothy R. Hughes, Andrew Emili, Stephen Buratowski, Philip Hieter, Jack Greenblatt   +13 more
openalex   +1 more source

Metabolic Regulation of Histone Acetyltransferases by Endogenous Acyl-CoA Cofactors. [PDF]

Chem Biol, 2015
Montgomery DC, Sorum AW, Guasch L, Nicklaus MC, Meier JL.   +4 more
europepmc   +1 more source

CEP162: A critical regulator of ciliary transition zone assembly and its implications in ciliopathies

Journal of Cell Communication and Signaling, Volume 19, Issue 2, June 2025.
Abstract CEP162, a 162‐kDa centrosome protein, is a crucial centrosomal adapter, mediating cell differentiation and polarization. CEP162 maintains mitosis by dynamically stabilizing microtubules. CEP162 promotes the transition zone (TZ) assembly in the basal body through interaction with CEP131, CEP290, and axoneme microtubules as well as the distal ...
Jun Yin, Jialian Bai, Xiaochong He, Wenjuan He, Hongming Miao, Mengjie Zhang, Zhongying Yu, Bing Ni   +7 more
wiley   +1 more source

Histone acetylation and histone acetyltransferases show significant alterations in human abdominal aortic aneurysm. [PDF]

Clin Epigenetics, 2016
Han Y, Tanios F, Reeps C, Zhang J, Schwamborn K, Eckstein HH, Zernecke A, Pelisek J.   +7 more
europepmc   +1 more source

Regulation of RhoB gene expression during tumorigenesis and aging process and Its potential applications in these processes [PDF]

, 2019
Bailey, Cedric A.R, et al,
core   +1 more source

Analysis of Nicotine Toxicity and Mechanisms of Senescence in Nucleus Pulposus Cells Using Network Toxicology and Molecular Docking Technique

JOR SPINE, Volume 8, Issue 2, June 2025.
The current study improves cyber toxicology as a method of evaluating environmental toxicity and molecular biological qualities in addition to clarifying the possible molecular pathways of nicotine‐induced senescence in IVDD. ABSTRACT Aim Through the use of network toxicology, the research sought to determine whether cellular senescence and associated ...
Chen Jiang, Chao Song, Chaoqi Chen, Baoxin Shen, Lei Yang, Chi Zhang, Fei Liu, Xiaofei Wu, Feng Chen   +8 more
wiley   +1 more source

Lactylation: From Homeostasis to Pathological Implications and Therapeutic Strategies

MedComm, Volume 6, Issue 6, June 2025.
Lactylation, a novel post‐translational modification derived from lactate metabolism, plays a critical role in cellular homeostasis and disease pathogenesis. Under physiological conditions, lactylation regulates gene expression, immune responses, and metabolic adaptation. However, dysregulated lactylation is implicated in various pathological processes,
Xi Chen, Yixiao Yuan, Fan Zhou, Lihua Li, Jun Pu, Yong Zeng, Xiulin Jiang   +6 more
wiley   +1 more source