Results 281 to 290 of about 223,415 (361)

Anti‐Tubercular Drug‐Induced Liver Injury: Current Understanding and Emerging Directions

JGH Open, Volume 10, Issue 1, January 2026.
ABSTRACT Most common adverse effect causing cessation of anti‐tubercular treatment (ATT) is drug‐induced liver injury (DILI) which is unpredictable due to its idiosyncratic nature. ATT is the most common cause of DILI and drug‐induced acute liver failure (ALF) in South East Asia.
Shubham Prasad, Himanshu Narang, Saurabh Kedia, Vineet Ahuja   +3 more
wiley   +1 more source

Metabolic Regulation of Histone Acetyltransferases by Endogenous Acyl-CoA Cofactors. [PDF]

Chem Biol, 2015
Montgomery DC, Sorum AW, Guasch L, Nicklaus MC, Meier JL.   +4 more
europepmc   +1 more source

Molecular Architecture of Quartet MOZ/MORF Histone Acetyltransferase Complexes

, 2008
Mukta Ullah, Nadine Pelletier, Lin Xiao, Songping Zhao, Kainan Wang, Cindy Degerny, Soroush Tahmasebi, Christelle Cayrou, Yannick Doyon, Siew-Lee Goh, Nathalie Champagne, Jacques Côté, Xiang-Jiao Yang   +12 more
openalex   +2 more sources

Acetylation of general transcription factors by histone acetyltransferases

Current Biology, 1997
A. Imhof, Xiang-Jiao Yang, V. Ogryzko, Y. Nakatani, A. Wolffe, H. Ge   +5 more
semanticscholar   +1 more source

The Role of Macrophages in Cancer: From Basic Research to Clinical Applications

MedComm, Volume 7, Issue 1, January 2026.
Monocytes infiltrate the tumor microenvironment (TME) and differentiate into macrophages, which polarize into proinflammatory, antitumor M1 cells or immunosuppressive, protumor M2 cells. Within the TME, M2‐type tumor‐associated macrophages (TAMs) predominate and drive tumor growth, angiogenesis, and metastasis. Therapeutic strategies therefore focus on
Zhimei Liu, Yan Li, Jingchao Cao, Yefeng Qiu, Kun Yu, Shoulong Deng   +5 more
wiley   +1 more source

Histone acetyltransferases are crucial regulators in NF-κB mediated inflammation.

Drug Discovery Today, 2011
M. Ghizzoni, H. Haisma, H. Maarsingh, F. Dekker   +3 more
semanticscholar   +1 more source

Breast Cancer: Molecular Pathogenesis, Targeted Therapy, Screening, and Prevention

MedComm, Volume 7, Issue 1, January 2026.
The review manuscript examines the molecular pathogenesis, screening, prevention advances, and evolving targeted therapies in breast cancer. It highlights the integration of AI and multiomics for precision prevention and personalized treatment, pointing toward future directions in equitable cancer care.
Huijun Lei, Jinzhen Fu, Wei Gu, Hongjin Qiao, Huixue Guo, Zijian Chen, San Ming Wang, Tianhui Chen   +7 more
wiley   +1 more source

TACC3 mediates the association of MBD2 with histone acetyltransferases: a novel mechanism for reactivation of methylated promoters

, 2006
Tiziana Angrisano
openalex   +1 more source

Perturbation of mitosis through inhibition of histone acetyltransferases: the key to ochratoxin a toxicity and carcinogenicity?

Toxicological Sciences, 2011
Kristin Czakai, Katja Müller, P. Mosesso, G. Pepe, M. Schulze, A. Gohla, D. Patnaik, W. Dekant, J. Higgins, A. Mally   +9 more
semanticscholar   +1 more source

Circular RNAs: Epigenetic Puppeteers Pulling the Strings of Cancer Pathogenesis

Medicine Bulletin, Volume 2, Issue 1, Page 124-136, January 2026.
ABSTRACT Circular RNAs (circRNAs), a unique class of endogenous noncoding RNAs characterized by their covalently closed loop structure, have emerged as pivotal players in cancer biology due to their exceptional stability, tissue‐specific expression, and diverse regulatory functions.
Yimao Wu, Zichang Chen, Junying Lee, Gokhan Zengin, Meng‐Yao Li   +4 more
wiley   +1 more source