Histone acetyltransferases - Open Access .click

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Copper induces histone hypoacetylation through directly inhibiting histone acetyltransferase activity

Chemico-Biological Interactions, 2004
The abnormal accumulation of Cu2+ is closely correlated with the incidence of different diseases, such as Alzheimer's disease and Wilson disease. To study in vivo functions of Cu2+ will lead to a better understanding of the nature of these diseases. In the present study, effect of Cu2+ on histone acetylation was investigated in human hepatoma cells ...
Jiuhong, Kang, Changjun, Lin, Jie, Chen, Qing, Liu +3 more
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Histone acetyltransferases in control.

Current biology : CB, 1997
Several transcriptional regulators have been found to act as enzymes that acetylate histones. The targeted post-translational modification of histones within regulatory nucleoprotein complexes provides an attractive mechanism for controlling transcription within a chromatin environment.
P A, Wade, A P, Wolffe
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Mammalian histone acetyltransferases and their complexes

Cellular and Molecular Life Sciences, 2001
One of the key questions in the current molecular genetics of eukaryotes is how genetic information is retrieved from tightly packed chromatin. Acetylation of core histone N-termini is implicated in the regulation of chromatin function, and I summarize what is known about the mammalian enzymes that promote this posttranslational histone modification ...
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Histone Acetyltransferases