Results 311 to 320 of about 223,415 (361)

NSD3S Promotes Cell Proliferation Through Stabilizing c‐Myc in Psoriatic Keratinocytes

open access: yesDermatologic Therapy, Volume 2026, Issue 1, 2026.
Histone methyltransferase nuclear receptor binding SET domain protein 3 (NSD3) has been reported to promote cell proliferation in a variety of cancer cells. However, whether NSD3 regulates cell proliferation in psoriatic cells is unknown. Here, we found elevated expression of NSD3S (the short isoform with no activity) but not NSD3L (the long isoform ...
Jinglin Xiong   +7 more
wiley   +1 more source

Immune System and Hepatic Stellate Cells’ Crosstalk in Liver Fibrosis: Pathways and Therapeutic Potential

open access: yesJournal of Immunology Research, Volume 2026, Issue 1, 2026.
Liver fibrosis, characterized by the excessive deposition of extracellular matrix (ECM) driven by hepatic stellate cells (HSCs) activation, remains a critical challenge due to its progression to cirrhosis and hepatocellular carcinoma (HCC). This review clarifies the complex crosstalk between the immune system and HSCs, highlighting key cellular players
Wahyu Widowati   +10 more
wiley   +1 more source

Molecular Insights Into Repurposed Drug Interactions With HDAC11 for Advancing Epigenetic Therapeutics in Cancer and Neurodegenerative Diseases

open access: yesJournal of Chemistry, Volume 2026, Issue 1, 2026.
Histone deacetylase 11 (HDAC11) is a member of the HDAC family that plays a crucial role in epigenetic regulation, influencing key cellular processes like transcription, differentiation, and proliferation. Abnormal expressions and functions of HDAC11 have been described in various diseases, including neurodegenerative diseases and cancer, highlighting ...
Yinsheng Yang   +5 more
wiley   +1 more source

Histone and non-histone (de)acetylation impact on the blood-brain barrier. [PDF]

open access: yesFluids Barriers CNS
Melo M   +3 more
europepmc   +1 more source

H3K14: A histone site closely related to diseases. [PDF]

open access: yesJ Cancer
Fan C   +6 more
europepmc   +1 more source

Regulation of Histone Acetylation During Inflammation Resolution. [PDF]

open access: yesImmunotargets Ther
Gong L   +7 more
europepmc   +1 more source

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