Results 331 to 340 of about 223,415 (361)
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Histone acetyltransferase activity in rat hepatomas

Journal of Cancer Research and Clinical Oncology, 1989
In view of various reports describing differences in histone acetylation between normal rat liver and hepatomas, the behaviour of histone acetyltransferase (EC 2.3.1.48) activity was elucidated in normal rat liver and in a spectrum of well-characterized rat hepatomas of slow, intermediate and rapid growth rates.
H H, Grunicke   +5 more
openaire   +2 more sources

The MYST Family of Histone Acetyltransferases

2003
Multiple chromatin modifying proteins and multisubunit complexes have been characterized in recent years. Histone acetyltransferase (HAT) activities have been the most thoroughly studied, both biochemically and functionally. This review sums up the current knowledge on a specific group of proteins that is extremely well conserved throughout evolution ...
R T, Utley, J, Côté
openaire   +2 more sources

Histone acetyltransferases and histone deacetylases of Physarum polycephalum

Cell Biology International Reports, 1992
Abstract DEAE-Sepharose chromatography of plasmodial extracts of the myxomycete Physarum polycephalum reveals the presence of multiple histone acetyltransferases and histone deacetylases. Five putative histone acetyltransferases and histone deacetylases.
G BROSCH   +5 more
openaire   +1 more source

Copper induces histone hypoacetylation through directly inhibiting histone acetyltransferase activity

Chemico-Biological Interactions, 2004
The abnormal accumulation of Cu2+ is closely correlated with the incidence of different diseases, such as Alzheimer's disease and Wilson disease. To study in vivo functions of Cu2+ will lead to a better understanding of the nature of these diseases. In the present study, effect of Cu2+ on histone acetylation was investigated in human hepatoma cells ...
Jiuhong, Kang   +3 more
openaire   +2 more sources

Histone acetyltransferases in control.

Current biology : CB, 1997
Several transcriptional regulators have been found to act as enzymes that acetylate histones. The targeted post-translational modification of histones within regulatory nucleoprotein complexes provides an attractive mechanism for controlling transcription within a chromatin environment.
P A, Wade, A P, Wolffe
openaire   +1 more source

Mammalian histone acetyltransferases and their complexes

Cellular and Molecular Life Sciences, 2001
One of the key questions in the current molecular genetics of eukaryotes is how genetic information is retrieved from tightly packed chromatin. Acetylation of core histone N-termini is implicated in the regulation of chromatin function, and I summarize what is known about the mammalian enzymes that promote this posttranslational histone modification ...
openaire   +2 more sources

Histone Acetyltransferases

2015
Yepeng Luan   +5 more
openaire   +2 more sources

Epigenetic Control of Oxidative Stresses by Histone Acetyltransferases in Candida albicans.

Journal of Microbiology and Biotechnology, 2018
Jueun Kim, Shinae Park, Jung-Shin Lee
semanticscholar   +1 more source

Modulation of cellular processes by histone and non-histone protein acetylation

Nature reviews. Molecular cell biology, 2022
Maria Shvedunova, A. Akhtar
semanticscholar   +1 more source

Histone Acetyltransferases in Cancer: Guardians or Hazards?

Critical reviews in oncogenesis, 2017
C. Demetriadou, A. Kirmizis
semanticscholar   +1 more source

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