Results 221 to 230 of about 1,862,085 (289)

Mass spectrometric analysis of global histone modification profiles during xenopus laevis development

, 2012
Tobias D. Schneider
openalex   +2 more sources

ChromNet: A Multi‐Task Learning Framework for Cross‐Cell Type Prediction of 3D Chromatin Interactions Using Epigenetic Signals

Advanced Science, EarlyView.
ChromNet enables accurate cross‐cell‐type prediction of chromatin architecture from DNA and epigenetic profiles alone, capturing both conserved and cell‐type‐specific (including disease‐associated) structural features. Its noise‐perturbed multi‐task learning design enhances generalization, enabling precise reconstruction of 3D genome organization even ...
Bin Wang, Shaokai Wang, Liqing Ding, Hongdong Li, Yaohang Li, Jianxin Wang   +5 more
wiley   +1 more source

The mechanism of histone modifications in regulating enzalutamide sensitivity in advanced prostate cancer. [PDF]

Int J Biol Sci
Zhao Z, Jing Y, Xu Z, Zhao H, He X, Lu T, Bai J, Qin W, Yang L.   +8 more
europepmc   +1 more source

Allele‐Specific Regulation of PAXIP1‐AS1 by SMC3/CEBPB at rs112651172 in Psychiatric Disorders Drives Synaptic and Behavioral Dysfunctions in Mice

Advanced Science, EarlyView.
This study identifies a functional noncoding variant, rs112651172 (C/G), that drives allele‐specific expression of PAXIP1‐AS1 in monozygotic twin pairs discordant for schizophrenia and bipolar disorder. The risk G allele enhances CEBPB binding, leading to lncRNA upregulation, CNTNAP3 derepression, and synaptic and behavioral deficits in mice.
Chaoying Ni, He Chen, Qiaqi Chen, Yangyang Liao, Yunqian Wang, Linyan Ye, Xiaohui Wu, Hongyu Ni, Tingyun Jiang, Shufen Li, Qiong Yang, Hong Xue, Zhongju Wang, Feng Yi, Cunyou Zhao   +14 more
wiley   +1 more source

DNA and Histone Modifications Identify a Putative Controlling Element (CE) on the X Chromosome of <i>Sciara coprophila</i>. [PDF]

Cells
Posukh OV, Shloma VV, Skrypnik PA, Maksimov DA, Antoshina PA, Kalashnikova DA, Nurislamov A, Lukyanchikova VA, Torgunakov N, Battulin NR, Fishman VS, Vyatkin YV, Smelova AA, Romanov SE, Laktionov PP, Valishayev D, Belyakin SN, Singh PB.   +17 more
europepmc   +1 more source

Multiscale Construction, Evaluation, and Application of Organoids

Advanced Science, EarlyView.
Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma, Zhenglin Dong, Zhu'anzhen Zheng, Long Bai, Xingcai Zhang, Jiacan Su   +5 more
wiley   +1 more source

An integrative multi-omics analysis of histone modifications and DNA methylation reveals the epigenomic landscape in apple under drought stress. [PDF]

Plant Biotechnol J
Wang S, He J, Hu B, Deng M, Li W, Guo J, Song Y, Zheng Q, Song X, Ma F, Wang J, Guan Q, Xu J.   +12 more
europepmc   +1 more source

OpEnHiMR: Optimization Based Ensemble Model for Prediction of Histone Modifications in Rice [PDF]

Dipro Sinha, Sneha Murmu, Girish Kumar Jha, Md Yeasin, Saikath Das, Sougata Bhattacharjee, Dwijesh Chandra Mishra, Neeraj Budhlakoti, Sudhir Srivastava, Sunil Archak   +9 more
openalex   +1 more source

Stage‐Resolved Phosphoproteomic Landscape of Mouse Spermiogenesis Reveals Key Kinase Signaling in Sperm Morphogenesis

Advanced Science, EarlyView.
The quantitative proteomic and phosphoproteomic profiling reveals dynamic phosphorylation regulation of sperm morphogenesis. Kinase‐substrate phosphorylation network and phosphorylation module analysis, followed by in vivo knockdown and knockout analysis, identify TTBK2 and CSNK1G1 as key regulators of morphogenesis, including head, flagellar, and ...
Tianyu Zhu, Yan Zhu, Xinyi Jiang, Xiangzheng Zhang, Bing Wang, Yu Chen, Yichen Zhao, Yulian Wang, Qi Zhou, Zhongyan Han, Yaling Qi, Mengjiao Luo, Haixia Tu, Bingjie Hao, Mengmeng Gao, Jie Ren, Xin Zhou, Xingyu Zhang, Xu Chen, Haojie Li, Qian Huang, Chenghao Situ, Yueshuai Guo, Hui Zhu, Yan Li, Xuejiang Guo   +25 more
wiley   +1 more source

A time-resolved atlas of histone modifications during mitotic entry

Kochanova NY, Borsò M, Deb M, Webb S, Ustun I, Samejima K, Forne I, Samejima I, Xie L, Paulson JR, Imhof A, Earnshaw WC.   +11 more
europepmc   +1 more source