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H1 histone variants in Xenopus laevis
Developmental Biology, 1981Abstract The H1 histones from erythrocytes, livers, intestines, testes, and embryos of Xenopus laevis have been examined electrophoretically. This species has been found to contain at least five electrophoretically resolvable lysine-rich histones in addition to the presumptive H5 histone of erythrocytes.
M S, Risley, R A, Eckhardt
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ASSEMBLY OF VARIANT HISTONES INTO CHROMATIN
Annual Review of Cell and Developmental Biology, 2005Chromatin can be differentiated by the deposition of variant histones at centromeres, active genes, and silent loci. Variant histones are assembled into nucleosomes in a replication-independent manner, in contrast to assembly of bulk chromatin that is coupled to replication.
Steven, Henikoff, Kami, Ahmad
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Environmental responses mediated by histone variants
Trends in Cell Biology, 2014Fluctuations in the ambient environment can trigger chromatin disruptions, involving replacement of nucleosomes or exchange of their histone subunits. Unlike canonical histones, which are available only during S-phase, replication-independent histone variants are present throughout the cell cycle and are adapted for chromatin repair.
Paul B, Talbert, Steven, Henikoff
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Histone variants in mouse centromeric chromatin
Molecular and Cellular Biochemistry, 1989Highly purified centromeric heterochromatin was isolated from mouse liver nuclei and the pattern of core histone variants was analyzed. In comparison with total chromatin, the centromeric heterochromatin of young animals was characterized by (1) enrichment in the replication-dependent variants H2A1, H2B2 and H3(2), (2) reduced amount of the minor ...
V, Russanova +3 more
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Histone H2A variants H2AX and H2AZ
Current Opinion in Genetics & Development, 2002Two of the nucleosomal histone families, H3 and H2A, have highly conserved variants with specialized functions. Recent studies have begun to elucidate the roles of two of the H2A variants, H2AX and H2AZ. H2AX is phosphorylated on a serine four residues from the carboxyl terminus in response to the introduction of DNA double-strand breaks, whether these
Christophe, Redon +5 more
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Histone variants during sea urchin development
Cell Biology International Reports, 1992The sea urchin genome contains several histone gene families whose expression is regulated in a developmental and tissue-specific fashion. The Cleavage Stage (CS) histone subtype is synthesized in unfertilized eggs and in embryos until the third cell cycle.
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SARS-CoV-2 variant biology: immune escape, transmission and fitness
Nature Reviews Microbiology, 2023Alessandro Maria Carabelli +2 more
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SARS-CoV-2 variant evasion of monoclonal antibodies based on in vitro studies
Nature Reviews Microbiology, 2022, William T Harvey, Joseph Hughes
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Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization
Nature, 2021Delphine Planas +2 more
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Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa
Nature, 2022Sikhulile Moyo +2 more
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