Results 211 to 220 of about 245,589 (335)

Reolysin and Histone Deacetylase Inhibition in the Treatment of Head and Neck Squamous Cell Carcinoma [PDF]

, 2017
Alena Cristina Jaime‐Ramirez, Jun-Ge Yu, Enrico Caserta, Ji Young Yoo, Jianying Zhang, Tae Jin Lee, Craig C. Hofmeister, John H. Lee, Bhavna Kumar, Quintin Pan, Pawan Kumar, Robert A. Baiocchi, Theodoros N. Teknos, Flavia Pichiorri, Balveen Kaur, Matthew Old   +15 more
openalex   +1 more source

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

Advanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You, Jaewoo Park, Jung Yeon Jang, Junho Noh, Jaehyun Lee, Geunho Kwon, Myeong Sang Yu, Yoo‐Sam Chung, Seung‐Jun Lee, Keunsoo Kang, Jihwan Park, Ji Heui Kim, Kyuho Kang   +12 more
wiley   +1 more source

Relationship of Circulatory Markers of NETosis with COVID-19 Severity: A Prospective Cohort Study. [PDF]

Indian J Crit Care Med
Kumar A, Kumar N, Banerjee A, Kumar A, Kumar A, Sinha C.   +5 more
europepmc   +1 more source

Histone Lys demethylase KDM3C demonstrates anti‐inflammatory effects by suppressing NF‐κB signaling and osteoclastogenesis [PDF]

, 2019
Jae Young Lee, Shebli Mehrazarin, Abdullah Alshaikh, Sol Kim, Wei Chen, Renate Lux, Yousang Gwack, Reuben H. Kim, Mo Kang   +8 more
openalex   +1 more source

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

Advanced Science, EarlyView.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang, Min Hu, Xia Wu, Mingwei Guo, Ying Ma, Jin Qiu, Siqi Wang, Yuxiang Cao, Yinzhao Zhong, Fangfang Chen, Yiwen Wang, Wei Wei, Yan Lu, Yong Zhang, Junjie Xiao, Zhenji Gan, Cheng Hu, Xinran Ma, Lingyan Xu   +18 more
wiley   +1 more source

Histone supply: a precious commodity for cell identity. [PDF]

Biochem J
Gonske S, Escobar TM, Loyola A.
europepmc   +1 more source

sNASP and ASF1A function through both competitive and compatible modes of histone binding [PDF]

, 2016
Andrew Bowman, Akiko Koide, Jay S. Goodman, Meaghan Colling, Daria Zinne, Shohei Koide, Andreas G. Ladurner   +6 more
openalex   +1 more source

Positive Feedback Loop of Histone Lactylation‐Driven HNRNPC Promotes Autophagy to Confer Pancreatic Ductal Adenocarcinoma Gemcitabine Resistance

Advanced Science, EarlyView.
Histone 3 lysine18 lactylation (H3K18la) drives heterogeneous nuclear ribonucleoprotein C (HNRNPC) overexpression, activating autophagy to mediate gemcitabine resistance by stabilizing TNF receptor‐associated factor 6 (TRAF6) mRNA. Concurrently, HNRNPC stabilizes aldehyde dehydrogenase 1 family member A3 (ALDH1A3) mRNA, which enhances glycolysis and ...
Xi‐Tai Huang, Jiao Chen, En‐Liang Zhu, Ming‐Jian Ma, Yang‐Yin‐Hui Yu, Ying‐Qin Zhu, Jing‐Yuan Ye, Jin‐Zhao Xie, Zi‐Yi Zhao, Xiao‐Yu Yin   +9 more
wiley   +1 more source

A method for cryo-EM analysis of eukaryotic nucleosomes reconstituted in bacterial cells. [PDF]

iScience
Ho CH, Kobayashi Y, Ogasawara M, Takizawa Y, Kurumizaka H.   +4 more
europepmc   +1 more source

Stat stimulates histone H3K4 methylation via KDM5 inhibition in adult stem cells of budding tunicates [PDF]

Yuri Kimura‐Nagano, Kenji Kishimoto, Satoko Sekida, Kaz Kawamura   +3 more
openalex   +1 more source