Results 211 to 220 of about 317,398 (334)

Post‐Translational Modifications in Cilia and Ciliopathies

Advanced Science, EarlyView.
This review synthesizes current understanding of post‐translational modifications (PTMs) in ciliary proteins and emphasizes their roles in ciliary formation, homeostasis, and signaling. This review also discusses the implication of PTM dysregulation in ciliopathies and explores therapeutic strategies targeting PTM‐modifying enzymes.
Jie Ran, Jun Zhou
wiley   +1 more source

Editorial: Molecular and Cellular Mechanisms in Reproduction and Early Development

Frontiers in Cell and Developmental Biology, 2019
Rafael A. Fissore, Adam Burton, Karin Lykke-Hartmann, Karin Lykke-Hartmann, Karin Lykke-Hartmann   +4 more
doaj   +1 more source

Histone Modifications: Potential Therapeutic Targets for Diabetic Retinopathy. [PDF]

Biomolecules
Lu Y, Zhang Y, Yao J, Bai W, Li K.
europepmc   +1 more source

CHANGING NUCLEAR HISTONE PATTERNS DURING DEVELOPMENT I. FERTILIZATION AND EARLY CLEAVAGE IN THE CRAB, EMERITA ANALOGA [PDF]

, 1968
Jack C. Vaughn
openalex   +1 more source

HISTONES AND DIFFERENTIATION [PDF]

Proceedings of the National Academy of Sciences, 1963
openaire   +3 more sources

LEDGF Binds H3R17me2a Promoting De Novo Nucleotide Biosynthesis in SETD2 Mutant Clear Cell Renal Cell Carcinoma

Advanced Science, EarlyView.
In SETD2‐mutant ccRCC, the original LEDGF recognition of the H3K36me3 regulatory axis no longer exists. LEDGF interacts with CARM1‐dependent H3R17me2a regulating the transcription of key enzymes in the de novo synthesis pathway. The abnormally elevated LEDGF leads to the accumulation of purine nucleotides in SETD2‐mutant ccRCC, thereby satisfying the ...
Yuwei Zhang, Yuhua Zhou, Yuezhou Zhang, Jing Lv, Yang Shen, Dong Zhang, Bo Liu, Wei Zhao, Junyi Ju, Qingyi Zhu, Ke Wang, Ninghan Feng   +11 more
wiley   +1 more source

ON THE ROLE OF HISTONES IN REGULATING RIBONUCLEIC ACID SYNTHESIS IN THE CELL NUCLEUS

, 1963
V. G. Allfrey, Virginia C. Littau, A. E. Mirsky   +2 more
openalex   +1 more source

Small RNA Toxin‐Assisted Evolution of GC‐Preferred ErCas12a for Enhanced Genome Targeting Range

Advanced Science, EarlyView.
ErCas12a is engineered to target GC‐rich PAMs using a small RNA toxin‐aided positive screening system. The resulting variant, enErCas12a, exhibits an expanded PAM profile and facilitates efficient gene editing in both bacterial and mammalian cells, while preserving high targeting specificity for both canonical and non‐canonical PAM targets.
Zehua Chen, Junyuan Xue, Ziying Wang, Jinyuan Sun, Yinglu Cui, Tong Zhu, Huaiyi Yang, Ming Li, Bian Wu   +8 more
wiley   +1 more source

Analysis of Treatment and Subsequent Pregnancy Outcomes in Patients With Antinuclear Antibody-Positive Recurrent Spontaneous Abortion. [PDF]

Immun Inflamm Dis
Wang A, Wu F, Liu M, Zhang Z, Li S, Tan Q.   +5 more
europepmc   +1 more source

Metabolism of Histones of Brain and Liver

, 1966
R. S. Piha, Michel Cuénod, Heinrich Waelsch   +2 more
openalex   +1 more source