Results 51 to 60 of about 100,216 (309)

Primary pupils' historical thinking [PDF]

open access: yes, 2012
PRIMARY PUPILSʼ HISTORICAL THINKING Abstract This thesis deals with development of childrenʼs historical thinking in primary school. At the beginning of the theses, changes in the Czech history curriculum are presented.
Kopecká, Karolína
core  

Core Concepts of Historical Thinking: Introduction

open access: yes, 2021
The paper is an introduction to the Historyka’s special issue about “Core Concepts of Historical Thinking.” It presents framework and assumptions which shape a profile and content of the volume. It shows understanding of “knowledge of the past” broader
Wiśniewski, Tomasz
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Implementation of Experiential Learning to Enhance Students' Historical Thinking Skills

open access: yesQalamuna
This study explores the implementation of Experiential Learning in enhancing students' historical thinking skills. Historical thinking is a critical competency that enables students to analyze, interpret, and critically evaluate historical events ...
Haris Firmansyah   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Bubbles and Bees: Historical Exploration of Psychosocial Thinking [PDF]

open access: yes, 2011
This paper is written from the belief that there is considerable benefit from ahistorical exploration of psychosocial thinking. It examines the work of BernardMandeville (1670-1733), who wrote what became an infamous piece of socialtheory in the early ...
Jones, David W.
core  

Intercultural Historical Thinking and its Sense in the History of Civilization

open access: yesHistória da Historiografia
This article explores the importance of intercultural historical thinking in the age of globalization and its significance to the historical study of civilization. The article points out that in the context of globalization, human beings are still faced
Yu Peiyun
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Historical Thinking Skills- The Forgotten Skills? [PDF]

open access: yes, 2015
This article explains the discipline structure of History subject in Malaysia. The discipline consists of five concepts: Historical Inquiry, Historical Information Gathering, Historical Thinking Skills (HTS), Historical Explanation, Understanding History
Rosy Talin
core   +1 more source

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