Results 41 to 50 of about 945,741 (291)
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
The Development of Historical Instruction/Teaching Material in Senior High Schools Based on Local History with SOI Approach [PDF]
, 2013 Purpose: The purpose of this research is to develop more comprehensive model of historical instructional materials that is a model of local history-based teaching materials and oriented to local historical events. The method used in the development
Djono,
core
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
2017 TASLAK TARİH 9-10-11, TÜRK KÜLTÜR ve MEDENİYET TARİHİ ÖĞRETİM PROGRAMLARININ ELEŞTİRİSİ
Turkish History Education Journal, 2017 2013 ve 2014’te TUBİTAK merkezli başlanan ve akîm kalan tarih program geliştirme çalışmaları dışında, 2015 yılında başlatılan ve 2016 yılında taslak olarak paylaşılan Tarih Öğretim Programı geliştirilmişti.
Ahmet ŞİMŞEK
doaj
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Changing conceptions of historical thinking in History education: an Australian case study
Tempo e Argumento, 2014 Many nations have experienced conflict over the content of their History curriculum, and debates over the relative importance of skills (historical thinking) versus content (historical knowledge). Australia is no exception. This paper seeks to contribute
Robert J. Parkes, Debra Donnelly
doaj +1 more source
Kaupapa Māori and a new curriculum in Aotearoa/New Zealand [PDF]
, 2010 While geographical education is our focus in this paper, the broader colonial history of education is the backdrop against which we first view the principles of Māori geographies in education.
Chalmers, Lex +1 more
core
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Persons-centered History and the Field of Curriculum
Journal of Curriculum Theorizing, 2018 n ...
Robert V. Bullough, Jr.
doaj +1 more source