Results 51 to 60 of about 6,071,151 (314)

The Expanding Environments Curriculum in America\u27s First Primary Schools [PDF]

open access: yes, 2009
This paper shows how America\u27s first educators rejected traditional biblical and classical material and introduced a citizenship curriculum that emphasized more personal and current topics.
Schwartz, Sherry
core  

History education in Nigeria: Past, present and future

open access: yesHistorical Encounters: A Journal of Historical Consciousness, Historical Cultures, and History Education, 2014
Before and after the introduction of western education to Nigeria by Christian missionaries, the teaching and learning of history was given pride of place, although the contents of school history privileged the Bible and English history by celebrating ...
Akanbi, Grace, Jekayinfa, Alice
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

What does the review of the Australian Curriculum mean for History in the Primary Years? [PDF]

open access: yes, 2015
The recent introduction of the Australian Curriculum: History as a timetabled school subject has enhanced the teaching of history in the primary years. Previously, history was integrated with geography, economics and civics and citizenship; however, in ...
Tambyah, Mallihai
core  

The Middle Ground of Curriculum: History Teachers’ Experiences in Ghanaian Senior High Schools

open access: yesAfrican Journal of Teacher Education, 2019
This study explores Ghanaian history teachers’ experiences of the "middle ground of curriculum; a crucial stage of curriculum negotiation and a process, according to  Harris (2002), that includes what “teachers individually and collectively perceived and
Charles Adabo Oppong   +2 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Enhancing reflective thinking through active learning: a study on eighth-level undergraduate students in the history program

open access: yesCogent Education
Reflective thinking skills are critical for students’ academic and professional development, enabling them to analyze information, evaluate arguments, and propose meaningful solutions.
Amal Saeed Ali Al-Qahtani   +1 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

The Curious Recent History of the Official Social Studies Curriculum in Arizona [PDF]

open access: yes, 2009
The rapid (and largely unanticipated) advance of national standards projects in various content fields over the past decade has led to a reexamination of those fields\u27 development over time, particularly at the state and national levels.
Robinson, Paul
core  

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