Results 141 to 150 of about 3,675 (177)

The effect of combining HIV latency reversal with inhibition of phosphoinositide-3 kinases or B-cell lymphoma-2 on the HIV reservoir. [PDF]

PLoS Pathog
Kim Y, Anderson JL, Tumpach C, Solomon A, Ong J, Tanaka K, Zerbato JM, Tan T, Teh CE, Gray DHD, Arandjelovic P, McMahon J, Meagher N, Price D, Pellegrini M, Roche M, Lewin SR.   +16 more
europepmc   +1 more source

Block-and-Lock Approaches for HIV Cure: Mechanistic Insights, Challenges, and Emerging Role of CPSF6. [PDF]

Int J Mol Sci
Tolomeo M, Cascio A.
europepmc   +1 more source

Inflammation and RONS Dysregulation by Redox Enzymes as Mechanistic Links in HIV-1-Cancer Comorbidity. [PDF]

Pathogens
Ang CG, Eyunni S, Chaiken IM.
europepmc   +1 more source

Harziachalasins A-G, polycyclic-fused cytochalasins from the endophytic fungus Trichoderma harzianum MLJ-4 with HIV latency reversal activity. [PDF]

Nat Prod Bioprospect
Zhang YJ, Yang XY, Fu YF, Liao Q, Chen JQ, Chen XA, Huang D, Yuan T, Chen X, Yin S, Tang GH.   +10 more
europepmc   +1 more source

Methaneseleninic acid, a circadian-modulating agent, reactivates latent HIV-1 infection without cellular activation or proliferation. [PDF]

J Virol
Stern J, Shepherd RA, Kim Y, Tumpach C, Amos KE, Williams OHL, Varshney S, King HAD, Rhodes A, Lewin SR, Roche M.   +10 more
europepmc   +1 more source

Network Pharmacology-Guided Identification of <i>Candida albicans</i> Secondary Metabolites as Modulators of HIV Latency via Oncogenic Signaling Pathways. [PDF]

Int J Mol Sci
Oduro-Kwateng E, Anyaneji UJ, Fanele A, Ntanzi N, Soliman ME, Mkhwanazi NP.   +5 more
europepmc   +1 more source

Solving a BAF'ling Problem : pharmacological Reversal of HIV-1 Latency

, 2019
openaire   +1 more source

Novel Latency Reversal Agents for HIV-1 Cure [PDF]

Annual Review of Medicine, 2018
Antiretroviral therapy (ART) has rendered HIV-1 infection a treatable illness; however, ART is not curative owing to the persistence of replication-competent, latent proviruses in long-lived resting T cells. Strategies that target these latently infected cells and allow immune recognition and clearance of this reservoir will be necessary to eradicate ...
Adam M Spivak, Vicente Planelles
exaly   +3 more sources

HIV-1 Latency and Latency Reversal: Does Subtype Matter? [PDF]

Viruses, 2019
Cells that are latently infected with HIV-1 preclude an HIV-1 cure, as antiretroviral therapy does not target this latent population. HIV-1 is highly genetically diverse, with over 10 subtypes and numerous recombinant forms circulating worldwide. In spite of this vast diversity, much of our understanding of latency and latency reversal is largely based
Indra Sarabia, Alberto Bosque, Bosque Alberto   +2 more
exaly   +3 more sources