Results 111 to 120 of about 30,666,235 (182)

Exploring potential associations between the human microbiota and reservoir of latent HIV

Retrovirology
Background The rapid establishment and persistence of latent HIV-1 reservoirs is one of the main obstacles towards an HIV cure. While antiretroviral therapy supresses viral replication, it does not eradicate the latent reservoir of HIV-1-infected cells ...
Nel Marín-Sánchez, Roger Paredes, Alessandra Borgognone   +2 more
doaj   +1 more source

HIV-1 persistence in the CNS: Mechanisms of latency, pathogenesis and an update on eradication strategies. [PDF]

Virus Res, 2021
Sonti S, Sharma AL, Tyagi M.
europepmc   +1 more source

Early pandemic HIV-1 integration site preferences differ across anatomical sites

Communications Medicine
Background HIV-1 persists in the body even when treatment suppresses viral replication. This persistence is due in part to the virus integrating into the DNA of infected cells.
Hinissan P. Kohio, Hannah O. Ajoge, Emile A. Barua, Neel R. Vajaria, Isaac K. F. Wu, Macon D. Coleman, Sean K. Tom, Frank van der Meer, John Gill, Deirdre Church, Paul Beck, Christopher Power, Guido van Marle, Stephen D. Barr   +13 more
doaj   +1 more source

The Clonal Expansion Dynamics of the HIV-1 Reservoir: Mechanisms of Integration Site-Dependent Proliferation and HIV-1 Persistence. [PDF]

Viruses, 2021
Yeh YJ, Yang K, Razmi A, Ho YC.
europepmc   +1 more source

Media communication in HIV/AIDS and STI : young people perspectives

, 2011
Background: Although recent developments of antiretroviral drugs for treating HIV/AIDS appear promising, prevention of infection is the only safeguard; and the key factor to preventing infection, be it of HIV or any other sexually transmitted disease, is
Razaghi, Kazem (R20892)
core  

The relationship between HIV seroconversion illness, HIV test interval and time to AIDS in a seroconverter cohort. [PDF]

, 2003
Seroconversion illness is known to be associated with more rapid HIV disease progression. However, symptoms are often subjective and prone to recall bias.
UK Register of HIV Seroconverters, UK, Gillett, J, Tyrer, F, Porter, K, Walker, AS   +4 more
core  

Uncovering the impact of randomness in HIV hotspot formation: A mathematical modeling study.

PLoS Computational Biology
BackgroundHIV hotspots, regions with higher prevalence than surrounding areas, are observed across Africa, yet their formation and persistence mechanisms remain poorly understood.
Nao Yamamoto, Daniel T Citron, Samuel M Mwalili, Duncan K Gathungu, Diego F Cuadros, Anna Bershteyn   +5 more
doaj   +1 more source

Tracking HIV persistence across T cell lineages during early ART-treated HIV-1-infection using a reservoir-marking humanized mouse model

Nature Communications
Human immunodeficiency virus (HIV) infection depletes CD4 T-cells, and long-term persistence of latent virus prevents full clearance of HIV even in the presence of effective antiretroviral therapy (ART), Here we present the HIV-1-induced lineage tracing (
Namita Satija, Foramben Patel, Gerrit Schmidt, Donald V. Doanman, Manav Kapoor, Annalena La Porte, Ying-Chih Wang, Kenneth M. Law, Anthony M. Esposito, Kimaada Allette, Kristin G. Beaumont, Robert P. Sebra, Benjamin K. Chen   +12 more
doaj   +1 more source

HIV-1 Persistence and Chronic Induction of Innate Immune Responses in Macrophages. [PDF]

Viruses, 2020
Akiyama H, Gummuluru S.
europepmc   +1 more source

Transcription factor BACH2 shapes tissue-resident memory T cell programs to promote HIV-1 persistence. [PDF]

Immunity
Wei Y, Ma HK, Wong ME, Back H, Papasavvas E, Mounzer K, Aberra F, Morgenstern R, Tebas P, Konnikova L, Montaner LJ, Ho YC.   +11 more
europepmc   +1 more source