Results 161 to 170 of about 30,666,235 (182)

Hide-and-Seek: The Challenge of Viral Persistence in HIV-1 Infection

Annual Review of Medicine, 2008
The success of highly active antiretroviral therapy (HAART) for HIV-1 infection has sparked interest in mechanisms by which the virus can persist despite effectively suppressive therapy. Latent HIV-1 reservoirs established early during infection not only prevent sterilizing immunity but also represent a major obstacle to virus eradication.
Luc, Geeraert, Günter, Kraus, Roger J, Pomerantz   +2 more
openaire   +2 more sources

Animal models of HIV-1 latency and persistence.

Current opinion in HIV and AIDS, 2009
In this review we address the animal models currently in use to study HIV-1 latency and persistence. We outline the rationale behind each model, the major scientific findings made, and discuss the extent of their relevance to HIV-1.Several animal models have allowed the complex area of viral latency to be studied in vivo. These models are, by necessity,
Helen J, Brown, Jerome A, Zack
openaire   +1 more source

Harnessing natural killer cells to target HIV-1 persistence

Current Opinion in HIV and AIDS
Purpose of review The purpose of this article is to review recent advances in the role of natural killer (NK) cells in approaches aimed at reducing the latent HIV-1 reservoir. Recent findings Multiple approaches to eliminate cells harboring latent HIV-1 are being explored, but have ...
Vinita R, Joshi, Marcus, Altfeld
openaire   +2 more sources

Persisting HIV-1 Replication Triggered by Acute Hepatitis a Virus Infection

Antiviral Therapy, 2000
We report the case of two patients in whom acute hepatitis A was associated with a marked and prolonged increase in human immunodeficiency virus type 1 (HIV-1) viral load. Although in one patient the rise in HIV-1 RNA might also have been related to the interruption of antiretroviral therapy, we also observed a similar pattern in the other patient who ...
A. L. Ridolfo, S. Rusconi, S. Antinori, C. Balotta, M. Galli   +4 more
openaire   +3 more sources

Persistent B19 parvovirus infections in hemophilic HIV‐1 infected patients

Journal of Medical Virology, 1995
AbstractB19 infection can be acquired by transmission with blood factors in patients with congenital bleeding disorders, requiring clotting factor concentrates. In immunodeficient patients, the failure of immunity to clear B19 virus may produce persistent infections.
M Musiani, M Zerbini, G Gentilomi, G Rodorigo, V De Rosa, D Gibellini, S Venturoli, G Gallinella   +7 more
openaire   +2 more sources

Persistent inflammatory markers existing with HIV-1 reservoirs in antiretroviral therapy treated HIV-1 individuals

Cytokine
Despite successful viral suppression with antiretroviral therapy, individuals infected with human immunodeficiency virus type 1(HIV-1) develop chronic inflammation, which may be related to immune activation due to the persistence of the viral reservoir. However, the mechanisms linking HIV-1 reservoirs to inflammation are not fully understood.
Yu, Shi, Chengchao, Ding, Zhi, Zhang, Tingting, Zhang, Jiamin, Liu, Lina, Huang, Xiangyu, Zhang, Rishen, Liang, Qin, Fang, Chenxi, Shuai, Jin, Zhang, Seying, Dai, Hongliang, He, Yong, Gao, Jianjun, Wu   +14 more
openaire   +2 more sources

One-year statin persistence and adherence in adults with HIV in the United States

Journal of Clinical Lipidology, 2021
Kaylee B Crockett, Lisandro D Colantonio, Edgar Overton   +2 more
exaly  

Single-cell multiomics reveals persistence of HIV-1 in expanded cytotoxic T cell clones

Immunity, 2022
Pablo Tebas, Neal G Ravindra, Serena Spudich   +2 more
exaly  

First International Workshop on HIV-1 Persistence During Therapy

HIV Clinical Trials, 2004
Roger, Pomerantz, Alain, Lafeuillade
openaire   +2 more sources

Patient adherence and persistence with oral anticancer treatment†

Ca-A Cancer Journal for Clinicians, 2009
Erica L Mayer, Kathryn J Ruddy, Ann Partridge   +2 more
exaly