Results 11 to 20 of about 138,358 (278)
Animal models for HIV cure research [PDF]
Frontiers in Immunology, 2016 The HIV-1/AIDS pandemic continues to spread unabated worldwide and no vaccine exists within our grasp. Effective antiretroviral therapy (ART) has been developed, but ART cannot clear the virus from the infected patient.
Ben Bruno Policicchio +2 more
doaj +5 more sources
Time to Engage Young People in HIV Cure Research. [PDF]
AIDS Res Hum Retroviruses, 2022 Antiretroviral treatments successfully suppress and control HIV but cannot eliminate the virus. In recent years, much research has gone into developing a cure for HIV. This research comes with significant risks and limited clinical benefits to study participants.
Saberi P +3 more
europepmc +6 more sources
Informed consent to HIV cure research [PDF]
Journal of Medical Ethics, 2017 Trials with highly unfavourable risk–benefit ratios for participants, like HIV cure trials, raise questions about the quality of the consent of research participants.
Bromwich, Danielle, Millum, Joseph R.
core +3 more sources
HIV cure research: a formidable challenge
Journal of Virus Eradication, 2015 The ultimate goal of HIV cure research is to allow HIV-infected individuals to be free of disease in the absence of antiretroviral therapy. We discuss current directions and future opportunities aimed at achieving sustained virological remission, and ...
Jintanat Ananworanich, Anthony S. Fauci
doaj +3 more sources
Animal models in HIV cure research
Journal of Virus Eradication, 2015 Current HIV antiretroviral therapy (ART) successfully inhibits viral replication in the majority of HIV-infected individuals. However, ART is not curative and lifelong adherence is required.
Luca Micci +2 more
doaj +3 more sources
Nonhuman Primate Models for HIV Cure Research [PDF]
PLoS Pathogens, 2012 1 Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, 2 Department of Microbiology and Molecular Genetics, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, 3 Department of Pathology, School of Medicine, University of Pittsburgh, Pittsburgh ...
Cristian Apetrei +3 more
core +7 more sources
Journal of Virus Eradication, 2019 The literature on HIV therapeutics research is rife with terminology associating ‘sterilisation’ with HIV cure. We find connotations of the word ‘sterilising’ problematic for the HIV cure research field.
Luke Newton +10 more
doaj +3 more sources
Unwillingness of patients in Ghana to interrupt antiretroviral therapy for HIV cure research. [PDF]
J Virus Erad, 2021 Bonney EY +10 more
europepmc +2 more sources
Healthcare Provider Perspectives on HIV Cure Research in Ghana. [PDF]
AIDS Res Treat, 2023 Introduction. Antiretroviral therapy (ART) has reduced mortality and improved life expectancy among HIV patients but does not provide a cure. Patients must remain on lifelong medications and deal with drug resistance and side effects. This underscores the need for HIV cure research.
Lamptey H +8 more
europepmc +5 more sources
Cancer therapies in HIV cure research. [PDF]
Curr Opin HIV AIDS, 2017 This article provides an overview of anticancer therapies in various stages of clinical development as potential interventions to target HIV persistence.Epigenetic drugs developed for cancer have been investigated in vitro, ex vivo and in clinical trials as interventions aimed at reversing HIV latency and depleting the amount of virus that persists on ...
Rasmussen TA +3 more
europepmc +6 more sources