Results 11 to 20 of about 4,065,904 (216)

Surfactant protein D binds to human immunodeficiency virus (HIV) envelope protein gp120 and inhibits HIV replication

Journal of General Virology, 2005
The envelope protein (gp120) of human immunodeficiency virus (HIV) contains highly conserved mannosylated oligosaccharides. These glycoconjugates contribute to resistance to antibody neutralization, and binding to cell surface lectins on macrophages and ...
Joseph Meschi, Tornoe, Ida, Khabirah Yahya, Paul Skolnik, Ida Tornoe, White, Mitchell R, Skolnik, Paul, Meschi, Joseph, Uffe Holmskov, Erika C. Crouch, Rikke Leth-Larsen, Leth-Larsen, Rikke; id_orcid, Kevan L. Hartshorn, Hartshorn, Kevan L, Crouch, Erika C, Holmskov, Uffe, Tecle, Tesfaldet, Tesfaldet Tecle, Mitchell R. White, Yahya, Khabirah   +19 more
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Surfactant protein D inhibits HIV-1 infection of target cells via interference with gp120-CD4 interaction and modulates pro-inflammatory cytokine production [PDF]

, 2014
© 2014 Pandit et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Al-Mozaini, MA, Pandit Hrishikesh, Yadav Ajit Kumar, Gopal, S, Idicula-Thomas, S, Uday Kishore (504246), Al-Mozaini Maha Ahmed, Vijay Kulkarni, Himangi Warke, Gopal Sandhya, Asif S Qaseem, Sonawani, A, Kulkarni, V, Warke Himangi, Hrishikesh Pandit, Patil, A, Himangi Warke (504243), Idicula-Thomas Susan, Anushree Patil (600836), Gajbhiye, R, Yadav, AK, Sandhya Gopal (600833), Kulkarni Vijay, Archana Sonawani (413679), Warke, H, Susan Idicula-Thomas, Taruna Madan, Sonawani Archana, Asif S. Qaseem, Maha Ahmed Al-Mozaini, Archana Sonawani, Hrishikesh Pandit (504240), Ajit Kumar Yadav (600834), Rahul Gajbhiye (600837), Qaseem, AS, Madan, T, Madan Taruna, Sandhya Gopal, Ajit Kumar Yadav, Qaseem Asif S., Gajbhiye Rahul, Rahul Gajbhiye, Patil Anushree, Pandit, H, Asif S. Qaseem (600835), Kishore Uday, Anushree Patil, Vijay Kulkarni (600838), Maha Ahmed Al-Mozaini (600839), Kishore, U, Taruna Madan (504241), Susan Idicula-Thomas (318974), Uday Kishore   +52 more
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HIV-gp120

, 2021
Deciphering the glycosylation of viral envelope (Env) glycoprotein is critical for evaluating viral invasion and the host’s immune response, and developing preventive vaccines and antiviral drugs.
Yong Zhang (9437864)
core   +1 more source

Induction of cytolytic T lymphocytes directed towards the V3 loop of the human immunodeficiency virus type 1 external glycoprotein gp120 by p55gag/V3 chimeric vaccinia viruses [PDF]

, 1993
T cell-mediated cytotoxicity may play an important role in controlling infection by human immunodeficiency virus (HIV). In order to study the ability of rationally designed antigens to induce cytolytic T lymphocytes (CTLs) we replaced stretches of 30 to ...
Deml, Ludwig, Böltz, T., Wagner, Ralf, Modrow, Susanne, Wolf, Hans J.   +4 more
core   +1 more source

Rescue of adult hippocampal neurogenesis in a mouse model of HIV neurologic disease

Neurobiology of Disease, 2011
The prevalence of central nervous system (CNS) neurologic dysfunction associated with human immunodeficiency virus (HIV) infection continues to increase, despite the use of antiretroviral therapy.
Myoung-Hwa Lee, Tongguang Wang, Mi-Hyeon Jang, Joseph Steiner, Norman Haughey, Guo-li Ming, Hongjun Song, Avindra Nath, Arun Venkatesan   +8 more
doaj   +1 more source

Super-resolution microscopy reveals specific recruitment of HIV-1 envelope proteins to viral assembly sites dependent on the envelope C-terminal tail [PDF]

, 2013
The inner structural Gag proteins and the envelope (Env) glycoproteins of human immunodeficiency virus (HIV-1) traffic independently to the plasma membrane, where they assemble the nascent virion. HIV-1 carries a relatively low number of glycoproteins in
Mike Heilemann, Barbara Müller, Walter Muranyi (212637), Malkusch, Sebastian, Müller, Barbara, Hans-Georg Kräusslich (7273), Walter Muranyi, Mike Heilemann (162287), Barbara Müller (212640), Sebastian Malkusch (383895), Muranyi, Walter, Hans-Georg Kräusslich, Kräusslich, Hans-Georg, Sebastian Malkusch, Heilemann, Mike   +14 more
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Binding of HIV-1 gp120 to DC-SIGN promotes ASK-1-dependent activation-induced apoptosis of human dendritic cells.

PLoS Pathogens, 2013
During disease progression to AIDS, HIV-1 infected individuals become increasingly immunosuppressed and susceptible to opportunistic infections. It has also been demonstrated that multiple subsets of dendritic cells (DC), including DC-SIGN⁺ cells, become
Yongxiong Chen, Shiuh-Lin Hwang, Vera S F Chan, Nancy P Y Chung, Shu-Rong Wang, Zhongye Li, Jing Ma, Chia-Wei Lin, Ya-Ju Hsieh, Kao-Ping Chang, Sui-Sum Kung, Yi-Chia Wu, Cheng-Wei Chu, Hsiao-Ting Tai, George F Gao, Bojian Zheng, Kazunari K Yokoyama, Jonathan M Austyn, Chen-Lung S Lin   +18 more
doaj   +1 more source

Effect of chloroquine on reducing HIV-1 replication in vitro and the DC-SIGN mediated transfer of virus to CD4⁺ T-lymphocytes

Retrovirology, 2007
Background Chloroquine (CQ) has been shown to inhibit HIV-1 replication in vitro as well as in vivo and has been proposed to alter the glycosylation pattern of the gp120 envelope.
Paxton William A, Pollakis Georgios, Baan Elly, Naarding Marloes A   +3 more
doaj   +1 more source

Novel Cell type-specific aptamer-siRNA delivery system for HIV-1 therapy [PDF]

, 2007
The successful use of small interfering RNAs (siRNAs) for therapeutic purposes requires safe and efficient delivery to specific cells and tissues. Here we demonstrate cell type-specific delivery of anti-HIV siRNAs via fusion to an anti-gp120 aptamer. The
Haitang Li, John Zaia, John Rossi, Jiehua Zhou, Shirley Li   +4 more
core   +1 more source

Positive In Vivo Selection of the HIV‐1 Envelope Protein gp120 Occurs at Surface‐Exposed Regions [PDF]

The Journal of Infectious Diseases, 2007
The rapid evolution of human immunodeficiency virus (HIV) envelope represents a major challenge to vaccine and drug development, particularly because the underlying mechanisms are not completely understood. To explore whether distinct patterns of positive selection within the envelope glycoprotein (gp) 120 exist and are associated with functionally ...
Joos, B, Fischer, M, Schweizer, A, Kuster, H, Böni, J, Wong, J K, Weber, R, Trkola, A, Gunthard, H F   +8 more
openaire   +4 more sources