PLoS ONE, 2012 Cell-mediated transmission and dissemination of sexually-acquired human immunodeficiency virus 1 (HIV-1) in the host involves the migration of immature dendritic cells (iDCs).
Anil Prasad +5 more
doaj +1 more source
Effect of naringin on gp120-induced injury mediated by P2X7 receptors in rat primary cultured microglia. [PDF]
PLoS ONE, 2017 Human immunodeficiency virus type-1 (HIV-1) envelope glycoprotein 120 has been shown to activate microglia, causing release of inflammatory and toxic factors.
Qiang Chen +8 more
doaj +1 more source
Role of the HIV-1 GP120 conserved domain 5 in envelope protein maturation and viral entry.
, 2007 Role of the HIV-1 GP120 conserved domain 5 in envelope protein maturation and viral ...
Jayita. Sen (7987124)
core +6 more sources
M‐tropic HIV envelope protein gp120 exhibits a different neuropathological profile than T‐tropic gp120 in rat striatum [PDF]
European Journal of Neuroscience, 2010 AbstractMost early human immunodeficiency virus type 1 (HIV‐1) strains are macrophage (M)‐tropic HIV variants and use the chemokine receptor CCR5 for infection. Neuronal loss and dementia are less severe among individuals infected with M‐tropic strains.
Alessia, Bachis +2 more
openaire +2 more sources
Role of the transcription factor E2F1 in CXCR4-mediated neurotoxicity and HIV neuropathology
Neurobiology of Disease, 2007 This study sought to determine the role of the transcription factor E2F1 in CXCR4-mediated neurotoxicity and HIV neuropathology. We studied the effect of the HIV envelope protein gp120 on the expression of E2F1-dependent apoptotic proteins in human and ...
Saori Shimizu +5 more
doaj +1 more source
Genetic and immunological characterization of new subtype G envelope expressing HIV-1 pseudoviruses [PDF]
, 2014 Includes bibliographical references.One of the greatest challenges for the development of an effective HIV-1 vaccine is the high genetic diversity of this pathogen and the complex escape mechanisms employed by the envelope gp120 and gp41 glycoprotein ...
Essomba, Rene Ghislain
core +1 more source
Generation and characterization of a bivalent protein boost for future clinical trials: HIV-1 subtypes CR01_AE and B gp120 antigens with a potent adjuvant. [PDF]
PLoS ONE, 2018 The RV144 Phase III clinical trial with ALVAC-HIV prime and AIDSVAX B/E subtypes CRF01_AE (A244) and B (MN) gp120 boost vaccine regime in Thailand provided a foundation for the future development of improved vaccine strategies that may afford protection ...
Yingxia Wen +38 more
doaj +1 more source
A single site for N-linked glycosylation in the envelope glycoprotein of feline immunodeficiency virus modulates the virus-receptor interaction [PDF]
, 2008 Feline immunodeficiency virus (FIV) targets helper T cells by attachment of the envelope glycoprotein (Env) to CD134, a subsequent interaction with CXCR4 then facilitating the process of viral entry.
Margaret J Hosie +14 more
core +1 more source
Amelioration of Neurotoxic Effects of HIV Envelope Protein gp120 by Fibroblast Growth Factor: A Strategy for Neuroprotection [PDF]
Journal of Neuropathology & Experimental Neurology, 2001 Approximately two thirds of patients with human immunodeficiency virus encephalitis (HIVE) show cognitive impairment and neurodegeneration, while one third are cognitively unimpaired and their neuronal populations are preserved. Thus, it is possible that these individuals might have the capacity to produce neurotrophic factors capable of protecting ...
Everall, I P +5 more
openaire +2 more sources
Assessment of HIV-1 entry inhibitors by MLV/HIV-1 pseudotyped vectors [PDF]
, 2005 Background: Murine leukemia virus (MLV) vector particles can be pseudotyped with a truncated variant of the human immunodeficiency virus type 1 (HIV-1) envelope protein (Env) and selectively target gene transfer to human cells expressing both CD4 and an ...
Sandra Siegert +11 more
core +1 more source