Results 131 to 140 of about 34,307 (290)

Biomaterial‐Integrated Electroporation for Therapeutic Delivery: From Gene Editing to Tumor Ablation and Immune Modulation

open access: yesSmall, EarlyView.
Biomaterial‐integrated electroporation establishes a programmable therapeutic interface that coordinates electric‐field modulation, transient or irreversible membrane permeabilization, cargo stabilization, and immune remodeling. This Review highlights how nanocarriers, hydrogels, and bioelectronic interfaces expand electroporation from conventional ...
Binbin Ji   +13 more
wiley   +1 more source

Unraveling the Physicochemical Landscape of Organoselenium Compounds in Nanocarrier Systems

open access: yesThe Chemical Record, EarlyView.
Main nanocarriers employed to enhance the bioavailability and transport of organoselenium compounds. The image illustrates the key interaction forces that stabilize these organoselenium species in solution, enabling their application in drug delivery systems, catalysis, photoelectronic devices, and sensing technologies. In recent years, publications on
Romelly Eugenia Rojas Ramírez   +3 more
wiley   +1 more source

Recent Advances in Photocatalyst‐Driven Protein Labeling and Proximity Mapping

open access: yesThe Chemical Record, EarlyView.
Photocatalyst‐driven protein labeling and proximity mapping have rapidly advanced as powerful strategies for spatiotemporal control in complex biological environments. This review integrates recent developments across single‐electron transfer and energy transfer‐based mechanisms and highlights how catalyst design, reactive intermediates, and diffusion ...
Shinichi Sato   +3 more
wiley   +1 more source

Structural and functional characterization of fatty acid-conjugated HIV fusion inhibitors.

open access: yes, 2019
The inhibitory activities of inhibitors on HIV-1HXB2 Env-mediated cell-cell fusion, HIV-1NL4-3(D36G) pseudovirus entry, and HIV-1JRCSF infection were respectively determined. The TRM sequence of T-20 is on italic. C16, palmitic acid; C24, lignoceric acid;
Ting Chen (15205)   +7 more
core   +1 more source

Nonthermal plasma approaches for combating implant‐associated infections: A compendious review

open access: yesVIEW, EarlyView.
Implant‐associated infections pose serious clinical challenges. Non‐thermal plasma (NTP) modifications overcome this bottleneck in distinct ways relative to traditional sterilization methods. Gas‐phase plasmas generate highly energetic species, UV radiation and reactive oxygen/nitrogen species (RONS), which alter the implant surface properties.
A. M. Trimukhe   +8 more
wiley   +1 more source

Fusion Inhibitors in HIV Infection

open access: yesDrugs in R & D, 1999
M, Wilde, R, Paterson
openaire   +2 more sources

The evolution of Australian cannabis policies, 1967 to 2024

open access: yesAddiction, EarlyView.
Abstract Aim To describe the outcomes of cannabis policy debates in Australia from 1967 to 2024. Methods We searched popular media, public reports, parliamentary inquiries and policy documents on cannabis in Australia since the 1960s and examined peer reviewed papers, national survey data and police records of cannabis‐related arrests.
Wayne D. Hall   +3 more
wiley   +1 more source

Synthesis and Study of Peptide analogs as HIV Fusion Inhibitors

open access: yes, 2010
Depuis la découverte du Virus de l'Immunodéficience Humaine (VIH) au début des années 80, la recherche de nouvelles molécules anti-VIH demeure un challenge important pour la communauté scientifique.
Baron, Alice
core  

Epidemiologia molecular do HIV-1 e resistência primária a antiretrovirais em indivíduos soropositivos da região metropolitana de Florianópolis/SC [PDF]

open access: yes, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Biotecnologia e BiociênciasFlorianópolis possui a segunda maior taxa de incidência de casos de AIDS entre as capitais brasileiras,
Gräf, Tiago
core  

A Proposed Clinical Diagnostic Framework for Short Telomere Syndrome

open access: yesClinical Genetics, EarlyView.
We propose a phenotype‐based diagnostic framework for short telomere syndrome that integrates age‐adjusted telomere length, phenotypic manifestations, and genetic findings, where available. The framework is intended to guide clinical evaluation, longitudinal surveillance, and individualized management while acknowledging limitations in current telomere
Andrew Courtwright   +8 more
wiley   +1 more source

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