Results 111 to 120 of about 34,307 (290)

Implantable drug delivery system: Frontiers of medicine‐engineering interdisciplinary

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the driving mechanisms of implantable on‐demand drug delivery systems (IDDS), including endogenous, exogenous, and closed‐loop strategies. It highlights the pivotal roles of flexible electronics and miniaturization in enhancing the tissue conformity and spatial adaptability.
Yu Zeng, Rongtai Su, Manyu Zhao, Xin Song, Ran Liu, Yuhao Zhou, Chaojuan Yang, Yanli Jiao, Xiao‐Wei Xiang, Lingqian Chang   +9 more
wiley   +1 more source

HIV-1 Entry Mechanisms: Protein-Host Receptor Interactions and Membrane Fusion Dynamics

Frontiers in Bioscience-Landmark
This review provides a comprehensive analysis of recent advancements in elucidating the molecular mechanisms underlying human immunodeficiency virus (HIV)-1 entry, focusing on the intricate interplay between the viral envelope glycoproteins (Env) and ...
Amir Elalouf, Hadas Elalouf, Hanan Maoz
doaj   +1 more source

Experiencing 50 Years of Synergistic Development in Structural Biology and Enzymology

Journal of the Chinese Chemical Society, EarlyView.
Picture of Sunney Chan with Academia Sinica (AS) President James C. Liao and three Vice Presidents: Shin‐Kun Peng (left one), Tang K. Tang (right one), and Mei‐Yin Chou (right 2), taken at the annual Chinese New Year's Banquet of AS, February 7, 2025. This was likely Sunney's last appearance in formal activities of AS.
Ming‐Daw Tsai
wiley   +1 more source

Peptide P5 (residues 628–683), comprising the entire membrane proximal region of HIV-1 gp41 and its calcium-binding site, is a potent inhibitor of HIV-1 infection

Retrovirology, 2008
The membrane proximal region (MPR) of the transmembrane subunit, gp41, of the HIV envelope glycoprotein plays a critical role in HIV-1 infection of CD4+ target cells and CD4-independent mucosal entry.
Clavel François, Labrosse Beatrice, Alfsen Annette, Tudor Daniela, Yu Huifeng, Bomsel Morgane   +5 more
doaj   +1 more source

Rational design of HIV vaccine and microbicides: report of the EUROPRISE annual conference. [PDF]

, 2010
EUROPRISE is a Network of Excellence sponsored from 2007 to 2011 by the European Commission within the 6th Framework Program. The Network encompasses a wide portfolio of activities ranging from an integrated research program in the field of HIV vaccines ...
Palma, Paolo, Palma Paolo, Lara Mainetti, Paolo Palma, Grupping, K., Reudelsterz, M., Robin Shattock, Hannes Uchtenhagen, Gabriella Scarlatti, Hallengärd, D, Uchtenhagen, H, Hallengärd David, Shattock Robin, Caroline Weber, Mainetti, Lara, Wahren, Britta, Winni De Haes, Coleman, A., Annette Sköld, Seifried, Janna, Sköld, A, Sköld Annette, Scarlatti, G, Lund University., Selhorst, P., Hornig Julia, van Gils, M. J., De Haes, W., Hornig, Julia, De Haes, W, Klein, K., Seifried Janna, Biswas, P., Da Costa, K., Da Costa Kelly, Da Costa, K, De Haes, Winni, Dieltjens Tessa, Wahren, B., Reudelsterz, Marc, Palma, P., Borggren, Marie,, Dispinseri Stefania, Seifried, J., Uchtenhagen, Hannes, Hornig, J., Borggren, Marie, Da Costa, Kelly, Scarlatti Gabriella, Selhorst, P, Wahren, B, Selhorst Philippe, David Hallengärd, Kelly Da Costa, Katrijn Grupping, Priscilla Biswas, Shattock, R., Katja Klein, Mainetti Lara, Mainetti, L., Janna Seifried, Dieltjens, Tessa, Scarlatti, Gabriella, Klein Katja, Marit J van Gils, Weber, Caroline, Weber, C, De Haes Winni, Uchtenhagen Hannes, Grupping Katrijn, van Gils, M.J., Borggren Marie, Adam Coleman, Weber Caroline, Shattock, R, Hornig, J, van Gils Marit J, Marie Borggren, Borggren, M, Selhorst, Philippe, Costa, Kelly Da, Mainetti, L, Skold, A., Biswas, P, Coleman, Adam, Coleman, A, Stefania Dispinseri, Gils, Marit J. van, Palma, P, Wahren Britta, Marc Reudelsterz, Hallengard, David, Seifried, J, Haes, Winni De, van Gils, MJ, Weber, C., Scarlatti, G., Philippe Selhorst, Biswas Priscilla, Reudelsterz, M, van Gils, Marit J., Klein, K, Hallengard, D., Britta Wahren, Tessa Dieltjens, Borggren, M., Dieltjens, T., Coleman Adam, Grupping, K, Biswas, Priscilla, Skold, Annette, Grupping, Katrijn, Dispinseri, S., Dieltjens, T, Dispinseri, S, Klein, Katja, Reudelsterz Marc, Julia Hornig, Dispinseri, Stefania, Shattock, Robin   +119 more
core   +1 more source

HPV‐6 Positive Eruptive Verruca Vulgaris After Upadacitinib Initiation for Severe Atopic Dermatitis

JEADV Clinical Practice, EarlyView.
ABSTRACT Oral JAK‐1 inhibitors for atopic dermatitis (AD) are associated with an increased risk of cutaneous viral infections, particularly herpes zoster. Emerging case reports further suggest a link to eruptive human papillomavirus (HPV) disease. A 23‐year‐old transgender man (female‐to‐male) with severe AD developed a rapidly disseminating eruption ...
Mohammed Shanshal, Emily Moon, Georgios Kallikas   +2 more
wiley   +1 more source

Human immunodeficiency virus : 25 years of diagnostic and therapeutic strategies and their impact on hepatitis B and C virus [PDF]

, 2009
The human immunodeficiency virus (HIV) had spread unrecognized in the human population as sexually transmitted disease and was finally identified by its disease AIDS in 1981.
Hans Wilhelm Doerr, Lutz Gürtler, Gürtler, Lutz, Stürmer, Martin, Doerr, Hans Wilhelm, Martin Stürmer   +5 more
core   +1 more source

Bevacizumab‐Associated Eczema Herpeticum in Metastatic Ovarian Carcinoma: A Case Report

JEADV Clinical Practice, EarlyView.
ABSTRACT Eczema herpeticum (EH) is a rare but potentially life‐threatening cutaneous infection caused by herpes simplex virus (HSV), classically associated with atopic dermatitis. Its occurrence in oncology patients receiving anti‐angiogenic targeted therapy and cytotoxic chemotherapy is exceedingly uncommon.
Mandeep Dutta Joshi, Nishant Pandey, Sushan Ghimire, Avilasha Shah, Anurag Tiwari, Salina Subedi, Deepika Neupane   +6 more
wiley   +1 more source

Class of antiretroviral drugs and the risk of myocardial infarction

, 2007
BACKGROUND:We have previously demonstrated an association between combination antiretroviral therapy and the risk of myocardial infarction. It is not clear whether this association differs according to the class of antiretroviral drugs.
El-Sadr, W, De Wit, S, Phillips, Andrew, Friis-Moller, Nina, Weber, R, Reiss, Peter, Lundgren, JD, O. Kirk, W. M. El Sadr, Monforte, AD, R. Thiébaut, El-Sadr, Wafaa, R. Weber, Friis-Moller, N, N. Friis Møller, Law, MG, Lundgren, Jens D., Kirk, O, Thiebaut, Rodolphe, Fontas, E, Friis-Møller, Nina, De Wit, Stephane, Sabin, Caroline, P. Reiss, S. De Wit, A. N. Phillips, Sabin, CA, d'Arminio Monforte, Antonella, Law, Matthew G., Reiss, P, E. Fontas, Sabin, Caroline A., Lundgren, Jens D, DAD Study Grp, Monforte, Antonella d'Arminio, Phillips, Andrew N., J. D. Lundgren, Phillips, A, Fontas, Eric, M. G. Law, Weber, Rainer, C. A. Sabin, Kirk, Ole, A. d’Arminio Monforte, Law, Matthew   +44 more
core   +1 more source

A Non‐Antigenic Randomized Polyethylene Glycol/Poly(2‐Phenyl‐2‐Oxazine)‐Based Drug Delivery Platform

Macromolecular Rapid Communications, EarlyView.
Randomized PEG (rPEG), a conceptually new PEG alternative, is combined with poly(2‐phenyl‐2‐oxazine) (PPheOzi) to establish an rPEG‐b‐PPheOzi‐b‐rPEG micellar drug delivery platform. The PPheOzi block enables high drug loadings, while competitive ELISA reveals a drastic reduction in anti‐PEG antibody affinity of rPEG in comparison to PEG.
Julian Schmidt, Anna‐Lena Ziegler, Florian T. Kaps, Laura J. Rosenberger, Matthias Bros, Holger Frey, Robert Luxenhofer   +6 more
wiley   +1 more source