SARS-CoV-2 Modulation of HIV Latency Reversal in a Myeloid Cell Line: Direct and Bystander Effects. [PDF]
Jarmoluk P +7 more
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A macrophage-cell model of HIV latency reveals the unusual importance of the bromodomain axis. [PDF]
Kisaka JK, Rauch D, Griffith M, Kyei GB.
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Defining the Effects of PKC Modulator HIV Latency-Reversing Agents on Natural Killer Cells. [PDF]
Dimapasoc M +8 more
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Three novel epigenetic-modifying compounds identified as HIV latency-reversing agents in Ghana
Abana CZ +13 more
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Integrated Single-cell Multiomic Analysis of HIV Latency Reversal Reveals Novel Regulators of Viral Reactivation. [PDF]
Ashokkumar M +11 more
europepmc +1 more source
Monocyte to macrophage differentiation and changes in cellular redox homeostasis promote cell type-specific HIV latency reactivation. [PDF]
Blanco A +5 more
europepmc +1 more source
CRISPR-Cas9 screen of E3 ubiquitin ligases identifies TRAF2 and UHRF1 as regulators of HIV latency in primary human T cells. [PDF]
Rathore U +20 more
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Epigenetic regulation of HIV latency
Current Opinion in HIV and AIDS, 2011A reservoir of latently infected cells remains in HIV-infected patients treated with highly active antiretroviral therapy treatment. Persistence of HIV in this latent reservoir has prevented full viral eradication. In order to understand and develop rational therapeutics to flush out HIV latency, the molecular mechanisms governing the phenomena of HIV ...
Shweta, Hakre +3 more
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This review describes some of the virus-cell relationships that might contribute to the state of latency observed in HIV infection. Viruses use many mechanisms to persist in their host, and the molecular interactions evoked by the virus and the cell on each other can influence the outcome of an infection.
D P, Bednarik, T M, Folks
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