PADI4-mediated citrullination of histone H3 stimulates HIV-1 transcription
Nature CommunicationsHIV-1 infection establishes a reservoir of long-lived cells with integrated proviral DNA that can persist despite antiretroviral therapy (ART). Certain reservoir cells can be reactivated to reinitiate infection.
Luca Love +6 more
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Role of long noncoding RNA in regulating HIV infection—a comprehensive review
mBioA complete cure against human immunodeficiency virus (HIV) infection remains out of reach, as the virus persists in stable cell reservoirs that are resistant to antiretroviral therapy.
Noa Amir, Ran Taube
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Experimental models for HIV latency and molecular tools for reservoir quantification-an update. [PDF]
Clin Microbiol Rev, 2023 Angamuthu D, Vivekanandan S, Hanna LE.
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The hypoxia-regulated ectonucleotidase CD73 is a host determinant of HIV latency. [PDF]
Cell Rep, 2023 Sperber HS +11 more
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HIV Latency and Nanomedicine Strategies for Anti-HIV Treatment and Eradication. [PDF]
Biomedicines, 2023 Andre M, Nair M, Raymond AD.
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Immune checkpoint inhibitors as potential therapy for reverting T-cell exhaustion and reverting HIV latency in people living with HIV. [PDF]
Front Immunol, 2023 Benito JM +3 more
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Discovering the Mechanisms of Oleodaphnone as a Potential HIV Latency-Reversing Agent by Transcriptome Profiling. [PDF]
Int J Mol Sci, 2023 Li S, Wang X, Yang Y, Wu X, Zhang L.
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HIV Latency in Myeloid Cells: Challenges for a Cure. [PDF]
Pathogens, 2022 Chitrakar A +3 more
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HSV-2 triggers upregulation of MALAT1 in CD4+ T cells and promotes HIV latency reversal. [PDF]
J Clin Invest, 2023 Pierce CA +13 more
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Secreted factors induced by PKC modulators do not indirectly cause HIV latency reversal. [PDF]
Virology, 2023 Moran JA +6 more
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