Results 141 to 150 of about 118,238 (222)

Prodrugs of γ-Alkyl-Modified Nucleoside Triphosphates: Improved Inhibition of HIV Reverse Transcriptase. [PDF]

Angew Chem Int Ed Engl, 2020
Zhao C, Weber S, Schols D, Balzarini J, Meier C.   +4 more
europepmc   +1 more source

Late diagnosis of paediatric HIV infection in high‐income countries: Lessons from the HIV Perinatal Virtual Clinic

HIV Medicine, Volume 27, Issue 3, Page 477-484, March 2026.
Abstract Introduction Timely diagnosis of HIV in children remains a challenge in all settings including low‐prevalence, high‐income countries (HIC). We aimed to characterize the prevalence of late diagnosis, and prior missed diagnostic opportunities among new presentations of paediatric HIV in HIC referred to an international Perinatal Virtual Clinic ...
Carolina Curto, M. Tritzali, A. Bamford, A. C. Bailey, E. G. H. Lyall, N. E. Mackie, N. Tickner, C. Foster, on behalf of the PVC   +8 more
wiley   +1 more source

Small Conformational Changes Underlie Evolution of Resistance to NNRTI in HIV Reverse Transcriptase. [PDF]

Biophys J, 2020
Srivastava A, Birari V, Sinha S.
europepmc   +1 more source

HIV reverse transcriptase [PDF]

Science-Business eXchange, 2014
openaire   +1 more source

Assessing subtypes and drug resistance mutations among HIV-1 infected children who failed antiretroviral therapy in Kelantan, Malaysia

Brazilian Journal of Infectious Diseases
Antiretroviral (ARV) therapy has dramatically reduced morbidity and mortality in human immunodeficiency virus 1 (HIV-1) infected children. However, development of ARV resistance in these children is a major public health problem due to lack of ...
Suharni Mohamad, Zakuan Zainy Deris, Nik Khairulddin Yusoff, Tg Ahmad Akram Tg Mohd Ariffin, Rafidah Hanim Shueb   +4 more
doaj   +1 more source

Click Chemistry-Based Two-Component System for Efficient Inhibition of Human Immunodeficiency Virus (HIV) Reverse Transcriptase (RT). [PDF]

ACS Omega, 2020
Ledezma CE, Cornett EM, Kolpashchikov DM.   +2 more
europepmc   +1 more source

Human Vault Nanoparticle Targeted Delivery of Antiretroviral Drugs to Inhibit Human Immunodeficiency Virus Type 1 Infection. [PDF]

, 2019
"Vaults" are ubiquitously expressed endogenous ribonucleoprotein nanoparticles with potential utility for targeted drug delivery. Here, we show that recombinant human vault nanoparticles are readily engulfed by certain key human peripheral blood ...
Anton, Peter A, Deming, Timothy, Elliott, Julie, Fulcher, Jennifer A, Ibarrondo, F Javier, Kickhoefer, Valerie A, Maynard, Heather D, Mrazek, Jan, Rome, Leonard H, Tamshen, Kyle, Wollenberg, Alexander L, Yang, Otto O   +11 more
core  

Exploring the Reaction Mechanism of HIV Reverse Transcriptase with a Nucleotide Substrate. [PDF]

J Phys Chem B, 2020
Wang H, Huang N, Dangerfield T, Johnson KA, Gao J, Elber R.   +5 more
europepmc   +1 more source

3-Hydroxypyrimidine-2, 4-dione Derivatives as HIV Reverse Transcriptase-Associated RNase H Inhibitors: QSAR Analysis and Molecular Docking Studies. [PDF]

Iran J Pharm Res, 2020
Mostoufi A, Chamkouri N, Kordrostami S, Alghasibabaahmadi E, Mojaddami A.   +4 more
europepmc   +1 more source

Fullerene Derivatives of Nucleoside HIV Reverse Transcriptase Inhibitors-In Silico Activity Prediction. [PDF]

Int J Mol Sci, 2018
Dąbrowska A, Pieńko T, Taciak P, Wiktorska K, Chilmonczyk Z, Mazurek AP, Stasiulewicz A.   +6 more
europepmc   +1 more source