Results 181 to 190 of about 1,155,481 (241)

Transmitted and pretreatment drug resistance among 69 HIV-1 CRFs in China: the first systematic analysis. [PDF]

Emerg Microbes Infect
Yin X, Zhao B, An M, Wang D, Liu Z, Shang H, Han X.   +6 more
europepmc   +1 more source

Profile of People Living with HIV Switching Prior Antiretroviral Treatment to a Doravirine-Based Regimen in the Real-World Clinical Setting in Greece: The Retrospective DORAVITO Study. [PDF]

Biomedicines
Papadopoulos A, Astriti M, Papastamopoulos V, Paparizos V, Sambatakou H, Metallidis S, Protopapas K, Moschopoulos C, Adamis G, Lourida P, Totsikas C, Vasalou V, Chrysanthidis T, Kollaras P, Boutselakou E, Tsokos D, Trimis G, Poughias L.   +17 more
europepmc   +1 more source

Novel Bridged Tricyclic Carbamoylpyridone Compounds as HIV Integrase Inhibitors for Treating HIV Infection. [PDF]

ACS Med Chem Lett
Sabnis RW.
europepmc   +1 more source

Phylogenetic Evidence of Local HIV-1 Transmission and Antiretroviral Drug Resistance in the Middle East and North Africa. [PDF]

Viruses
Al-Fraihat E, Irshaid A, Sallam M, Snygg J, Awawdeh R, Al-Shakerchi H, Al-Baidhani S, Sallam M.   +7 more
europepmc   +1 more source

High frequency of HIV-1 drug resistance among individuals with persistent low-level viremia during first-line antiretroviral therapy in Uganda. [PDF]

BMC Infect Dis
Sanyu G, Mayanja Y, Omooja J, Asio JN, Nannyonjo M, Ssemanda P, Hellen N, Ssewanyana I, Drago KC, Kaleebu P, Ssemwanga D.   +10 more
europepmc   +1 more source

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HIV nucleoside reverse transcriptase inhibitors

European Journal of Medicinal Chemistry, 2022
More than 40 years into the pandemic, HIV remains a global burden and as of now, there is no cure in sight. Fortunately, highly active antiretroviral therapy (HAART) has been developed to manage and suppress HIV infection. Combinations of two to three drugs targeting key viral proteins, including compounds inhibiting HIV reverse transcriptase (RT ...
Raymond Schinazi, Maryam Ehteshami, Eleftherios Michailidis   +2 more
exaly   +3 more sources

Specific HIV-1 Reverse Transcriptase Inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, 1992
Erik de Clercq, Zeger Debyser, K Andries   +2 more
exaly   +3 more sources

HIV-1 reverse transcriptase inhibitors

Applied Microbiology and Biotechnology, 2007
Reverse transcriptase (RT) is one of the three enzymes encoded by the human immunodeficiency virus type 1 (HIV-1), the etiological agent of AIDS. Together with protease inhibitors, drugs inhibiting the RNA- and DNA-dependant DNA polymerase activity of RT are the major components of highly active antiretroviral therapy (HAART), which has dramatically ...
El Safadi, Yazan, Vivet-Boudou, Valérie, Marquet, Roland   +2 more
openaire   +3 more sources

Fidelity of HIV-1 Reverse Transcriptase

Science, 1988
The human immunodeficiency virus type 1 (HIV-1) shows extensive genetic variation and undergoes rapid evolution. The fidelity of purified HIV-1 reverse transcriptase was measured during DNA polymerization in vitro by means of three different assays.
B D, Preston, B J, Poiesz, L A, Loeb
openaire   +2 more sources