Results 1 to 10 of about 83,958 (230)

Matching strategy for patients with platelet transfusion refractoriness caused by compound antibodies against HLA and CD36

Zhongguo shuxue zazhi, 2023
Objective To search compatible and suitable platelets for platelet transfusion refractoriness (PTR) patient caused by compound antibodies against HLA and CD36.
Jing DENG, Xiuzhang XU, Huibin ZHONG, Bi ZHONG, Yangkai CHEN, Jing LIU, Haoqiang DING, Wenjie XIA, Dawei CHEN, Yaori XU, Xin YE   +10 more
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HLA as risk and protection antigens against urinary tract diseases

Український Журнал Нефрології та Діалізу, 2022
. Currently, there is no doubt about the feasibility of determining the frequency of HLA and analysis of genetic associations, including those that determine the state of immunity, in patients with the genitourinary disease.
M. Kolesnyk, S. Vozianov, V. Driianska, O. Shulyak, I. Gorpynchenko, Yu. Bondarenko, M. Velychko, I. Petrina, V. Chernenko, D. Chernenko, T. Poroshina, K. Nurimanov   +11 more
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Chimerism Revisited: Perspective of an Immunopathologist [PDF]

Journal of Clinical and Diagnostic Research, 2023
Introduction: Chimerism analysis is an important diagnostic tool not only for assessing the risk of relapse after allo-Haematopoietic Stem Cell Transplant (HSCT) in patients with malignant diseases, it is also the predominant method for monitoring post ...
Devika Gupta, Lavan Singh, Kamlesh Kumar Singh, Tathagata Chatterjee   +3 more
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Allo-Specific Humoral Responses: New Methods for Screening Donor-Specific Antibody and Characterization of HLA-Specific Memory B Cells

Frontiers in Immunology, 2021
Antibody-mediated allograft rejection (AMR) causes more kidney transplant failure than any other single cause. AMR is mediated by antibodies recognizing antigens expressed by the graft, and antibodies generated against major histocompatibility complex ...
Shengli Song, Miriam Manook, Jean Kwun, Annette M. Jackson, Annette M. Jackson, Stuart J. Knechtle, Garnett Kelsoe, Garnett Kelsoe   +7 more
doaj   +1 more source

KIR and their HLA Class I ligands: Two more pieces towards completing the puzzle of chronic rejection and graft loss in kidney transplantation. [PDF]

PLoS ONE, 2017
Kidney transplantation is a life-saving treatment for patients with end-stage renal disease. However, despite progress in surgical techniques and patient management, immunological rejection continues to have a negative impact on graft function and ...
Roberto Littera, Gianbenedetto Piredda, Davide Argiolas, Sara Lai, Elena Congeddu, Paola Ragatzu, Maurizio Melis, Elisabetta Carta, Maria Benigna Michittu, Donatella Valentini, Luisella Cappai, Rita Porcella, Francesco Alba, Maria Serra, Valentina Loi, Roberta Maddi, Sandro Orrù, Giorgio La Nasa, Giovanni Caocci, Roberto Cusano, Marcella Arras, Mauro Frongia, Antonello Pani, Carlo Carcassi   +23 more
doaj   +1 more source

Consequence of Histoincompatibility beyond GvH-Reaction in Cytomegalovirus Disease Associated with Allogeneic Hematopoietic Cell Transplantation: Change of Paradigm

Viruses, 2021
Hematopoietic cell (HC) transplantation (HCT) is the last resort to cure hematopoietic malignancies that are refractory to standard therapies. Hematoablative treatment aims at wiping out tumor cells as completely as possible to avoid leukemia/lymphoma ...
Matthias J. Reddehase, Rafaela Holtappels, Niels A. W. Lemmermann   +2 more
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Expression of HLA class II molecules in humanized NOD.Rag1KO.IL2RgcKO mice is critical for development and function of human T and B cells. [PDF]

PLoS ONE, 2011
BACKGROUND: Humanized mice able to reconstitute a surrogate human immune system (HIS) can be used for studies on human immunology and may provide a predictive preclinical model for human vaccines prior to clinical trials. However, current humanized mouse
Rebecca Danner, Snehal N Chaudhari, John Rosenberger, Jacqueline Surls, Thomas L Richie, Teodor-Doru Brumeanu, Sofia Casares   +6 more
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HLA–D region antigens in patients with rheumatoid arthritis [PDF]

Arthritis & Rheumatism, 1991
AbstractWe studied the distribution of HLA–D region antigens in 2 groups of rheumatoid arthritis (RA) patients: those with mild, nonprogressive disease, and those with severe disease. The results demonstrate that DR4 was significantly increased in both RA patient populations.
C T, McCusker, B, Reid, D, Green, D D, Gladman, W W, Buchanan, D P, Singal   +5 more
openaire   +2 more sources

Donor HLA−DR Drives the Development of De Novo Autoimmunity Following Lung and Heart Transplantation

Transplantation Direct, 2020
Background. Individuals harbor preexisting HLA−DR/DQ−restricted responses to collagen type V (ColV) mediated by Th17 cells under Treg control, both specific to peptides that bind to inherited HLA class II antigens. Yet after transplant, the donor−DR type
Ewa Jankowska−Gan, MS, Vrushali V. Agashe, PhD, Diego A. Lema, MD, Ying Zhou, MS, Laura Gonzalez Bosc, PhD, Jeremy A. Sullivan, PhD, Daniel S. Greenspan, PhD, William J. Burlingham, PhD   +7 more
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Investigation of MHC gamma block C4A and C4B polymorphisms in unrelated hematopoietic stem cell transplantation

Hematology, Transfusion and Cell Therapy, 2020
Background: Immunological life-threatening complications frequently occur in post-hematopoietic stem cell transplantation (HSCT), despite matching recipient and donor (R/D) pairs for classical human leukocyte antigens (HLA).
Joselito Getz, Monica Goldenstein, Carmem Bonfim, Vaneuza Moreira Funke, Vergílio Colturato, Nelson Hamerschlak, Margareth Torres, David Sayer, Angelica Boldt, Ricardo Pasquini, Noemi Farah Pereira   +10 more
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