Results 111 to 120 of about 85,998 (151)

HLA‐D‐restricted Antigen Activation of Sensitized T Lymphocytes: Studies on the Ability of HLA‐D/DR‐expressing B Lymphocytes to Substitute for Macrophages in Antigen Activation

Scandinavian Journal of Immunology, 1979
The proliferative response of sensitized human T lymphocytes to purified protein derivative (PPD) and to trinitrophenyl (TNP)‐conjugated autologous cells in vitro is restricted by self HLA‐D/DR determinants. Here we report that the PPD‐specific response is strictly related to the content of phagocytosing celts (macrophages, M) in the cultures and that ...
B O, Bergholtz, E, Thorsby
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HLA-D Related Antigens in Inflammatory Bowel Disease

1981
There is good evidence that genetic as well as environmental factors are important in the aetiology of inflammatory bowel disease (1). However, studies of HLA-A and -B specificities have not shown consistent differences between patients and controls. Nevertheless an investigation of the HLA-D related [DR] antigens in such patients would be of interest ...
W. R. Burnham, K. Gelsthorpe, M. J. S. Langman   +2 more
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HLA–D and –DR antigens on human amniotic fluid cells

Tissue Antigens, 1983
Human amniotic fluid cells, known to express HLA–A, –B, and –C antigens, were tested for the presence of lymphocyte‐stimulating antigens (LD or HLA–D) using modifications of the mixed lymphocyte culture (MLC) and primed lymphocyte typing (PLT) tests. Peripheral blood lymphocytes were co‐cultured with various concentrations of allogeneic amniotic fluid ...
Elizabeth Valentine‐Thon, Gerlinde Kreeb, Hans Grosse‐Wilde, Eberhard Passarge   +3 more
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T cell clones restricted to "hybrid" HLA-D antigens?

The Journal of Immunology, 1982
Abstract The genetics of T lymphocyte/accessory cell interactions were studied by using antigen-specific monoclonal T cell lines from human peripheral blood and X-irradiated non-T cells (E rosette-depleted) as accessory cells. The T cell lines were obtained by expanding single colonies from soft agar-cloned E rosette-positive lymphocytes,
G S, Hansen, A, Svejgaard, M H, Claësson   +2 more
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The Frequencies of HLA-D Antigens in the Population of SR Croatia

1986
Despite of the significant correlation between the majority of serologicaly defined HLA-DR antigens and HLA-D antigens defined by homozygous typing cells (HTC), the correlation between HLA-Dw6/DRw6 and some newly defined HLA-D/DR antigens is rather low.
Marijan Gerenčer, Marija Tomašković, Slobodan Pfeifer, Vesna Mezulić, Andrija Kaštelan   +4 more
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Importance of HLA‐D antigens for the cooperation between human monocytes and T lymphocytes

European Journal of Immunology, 1978
AbstractThe ability of autologous and allogeneic monocytes to restore the responsiveness of purified T lymphocytes to tuberculin (PPD) was studied in twelve different experiments involving eleven unrelated T lymphocyte donors and a large number of related and unrelated monocyte donors.
G S, Hansen, B, Rubin, S F, Sørensen, A, Svejgaard   +3 more
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Evidence for Two Series of B‐Cell Antigens in Man and Their Comparison with HLA‐D

Scandinavian Journal of Immunology, 1977
Population mid family studies of five sera with antibodies against B‐cell determinants show an excellent fit of some of them with the HLA‐D determinants, suggesting that the HLA‐D determinants themselves or closely linked structures can be recognized by serology.
J J, van Rood, A, van Leeuwen, J J, Keuning, A, Termijtelen   +3 more
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Primed LD Typing: Reagent Preparation and Definition of the HLA‐D‐Region Antigens

Scandinavian Journal of Immunology, 1977
Primed LD typing cells were prepared against single HLA haplotypes within families and used to type a random panel of 48 individuals. PLT cells could be grouped on the basis of highly correlated responses with the panel test cells; the 21 different PLT cells could be used to define 6 different PL antigens. One of these, PL 3, was split by the responses
F H, Bach, E K, Jarrett-Toh, C J, Benike, C Y, Shih, E A, Valentine, P M, Sondel, M L, Bach   +6 more
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HLA‐D/DR Restriction of Macrophage‐dependent Antigen Activation of Immune T Lymphocytes: Cross‐reacting Allogeneic HLA‐D/DR May Partly Substitute for Self HLA‐D/DR

Scandinavian Journal of Immunology, 1980
Optimal proliferative response of T lymphocytes to purified protein derivative of tuberculin (PPD) III vitro requires that antigen be presented by autologous macrophages or allogeneic macrophages sharing HLA‐D/DR determinants with the T cell donor. In some cases, however, T cells may respond to a limited extent to PPD in association with macrophages ...
B O, Bergholtz, A B, Thoresen, E, Thorsby   +2 more
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HLA-DB3: population distribution and family studies of a new HLA-D antigen associated with HLA-D antigen associated with HLA-DR4 in Caucasoids.

Tissue antigens, 1983
On the basis of studies with 6 HTCs in four different families the new cluster DB3 identified in the 8th Workshop can be considered an established specificity of the HLA-D series. In 112 healthy Caucasoids resident in South East England the frequency of this antigen was 2.6% similar to the frequency found in 142 Caucasoid patients with rheumatoid ...
Jaraquemada, D, Ollier, William, Okoye, R, Sachs, J, Festenstein, H, Grosse-wilde, H   +5 more
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