Results 121 to 130 of about 83,958 (230)

Immunopeptidomics of cutaneous leishmaniasis patients reveals the natural antigenic landscape. [PDF]

Front Immunol
de Vrij N, Pepermans E, Laurijssen L, Pham TT, Thijs L, Boonen K, Ramadan K, Maes I, Aleka Y, Kassa M, Mekonnen T, Asres MS, Woldetensay M, Hassen S, Bialfew F, Tilahun Zewdu F, Abdela SG, Domagalska MA, Cuypers B, van Henten S, van Griensven J, Meysman P, Baggerman G, Laukens K, Adriaensen W.   +24 more
europepmc   +1 more source

Parkinson's‐Linked LRRK2 and GBA1 Mutations Modulate the Peripheral Immune Response to Pseudomonas aeruginosa

Movement Disorders, EarlyView.
Abstract Background Peripheral disease mechanisms such as immune dysregulation may contribute to Parkinson's disease (PD). To investigate interactions between common PD mutations and immune responses to environmental pathogens, we studied responses to Pseudomonas aeruginosa (P.
Julian R. Mark, Hannah A. Staley, Ann M. Titus, Julian Agin‐Liebes, Alicia Garrido, Laura Hughes, Nicolas Dzamko, Rebecca L. Wallings, Malú Gámez Tansey   +8 more
wiley   +1 more source

Optimisation and application of a T-cell antigen-specific activation assay as diagnostic and treatment-monitoring tool for tuberculosis. [PDF]

ERJ Open Res
Musvosvi M, Nemes E, Tameris M, Mendelsohn SC, Fisher M, Filander E, Visagie S, Africa H, Jaxa L, Mulenga H, Veldsman A, Hatherill M, Riou C, Via LE, Malherbe ST, Walzl G, Chen RY, Barry CE, Wilkinson RJ, Scriba TJ.   +19 more
europepmc   +1 more source

Respiratory Syncytial Virus (RSV): A Comprehensive Overview From Basic Biology to Clinical Prevention and Control

Medicinal Research Reviews, EarlyView.
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi, Xiya Huang, Chunjun Ye, Yishan Lu, Yanyan Liu, Yuquan Wei, Xiawei Wei   +6 more
wiley   +1 more source

HLA and T-Cell Receptor Investigations in Idiopathic and Paraneoplastic Opsoclonus-Myoclonus in Children. [PDF]

Neurol Neuroimmunol Neuroinflamm
Olivé-Cirera G, Muñoz-Sánchez G, Palou E, Ruiz García R, Fonseca EG, Luchoro JF, Aguilera-Albesa S, Maudes E, Martinez-Hernandez E, Sabater L, Dalmau JO, González A, Armangue T.   +12 more
europepmc   +1 more source

Mydriasis as a Secondary Effect in Patients With HLA‐B27–Associated Uveitis

Medicine Advances, EarlyView.
HLA‐B27‐associated acute anterior uveitis causes significant inflammation of the iris and anterior chamber, which disrupts normal parasympathetic control and results in increased sympathetic tone leading to pupil dilation (mydriasis). This finding can sometimes resemble herpetic uveitis, making a clinical context and careful evaluation crucial for ...
Saim Mahmood Khan, Menahil Faheem Siddiqui, Syeda Areesha Shoaib, Surraiya Riaz Mahmood Khan, Jawairya Muhammad Hussain, Syeda Faiqa Batool, Hudda Amjad   +6 more
wiley   +1 more source

The Drug Safety Framework of Avacopan: A Pharmacovigilance Study

Medicine Advances, EarlyView.
We identified 11 previously unreported potential adverse events associated with avacopan. No high‐priority clinical events were observed; however, special attention should be paid to the potential possibility of avacopan‐induced vanishing bile duct syndrome (Logos and icons displayed in the sections “Safety Framework” and “Data Sources and ...
Tianqi Chang, Xiaohong Xin, Xian Shao, Dikang Pan, Jingyu Wang   +4 more
wiley   +1 more source

AlloPipe and Its Web Server Allogenomics: From Genomic Data to Candidate Minor Histocompatibility Antigens. [PDF]

HLA
Dhuyser A, Delaugère P, Laville P, Clerc R, Aarnink A, Mesnard L, Richard H.   +6 more
europepmc   +1 more source

The Genomic Evolution of Early‐Stage Non‐Small Cell Lung Cancer

Medicine Advances, EarlyView.
This study provides a comprehensive overview of the genomic landscape of early‐stage non‐small cell lung cancer, identifying the 4q12 deletion as a potential exclusive biomarker for the “oncogenic switch” from pre‐invasive to invasive lesions. It delineates that while EGFR and TP53 mutations act as early truncal drivers, the progressive increase in ...
Huatao Tang, Yang Zhang, Haiquan Chen
wiley   +1 more source

Prediction of immunogenicity of Rh antigens using in silico analysis of binding to human leukocyte antigen peptide, Basic/Translational Research. [PDF]

PLoS One
Youk HJ, Cho YJ, Han YH, Kim SW, Ko DH.
europepmc   +1 more source