Results 111 to 120 of about 676,827 (333)

HLA and non-HLA polymorphisms in renal transplantation

Swiss Medical Weekly, 2012
Despite progress made in the field of immunosuppression, graft rejection remains a major cause of morbidity and mortality of patients after solid organ transplantation. There are several genetic causes which could influence the outcome of renal transplantation.
Laperrousaz, Stéphanie Lidia, Tiercy, Jean-Marie, Villard, Jean, Ferrari-Lacraz, Sylvie   +3 more
openaire   +4 more sources

Estudio de HLA en Amerindios Colombianos

Iatreia, 2013
INTRODUCCIÓN: Colombia es un país al norte de Suramérica y debido a esta posición privilegiada fue la entrada para la colonización española desde el siglo XVI al continente.
Carlos Parga Lozano, Paola Chamorro Alfaro, Leyla Montes Pacheco, Angie Laserna Moreno, Kelly García Herrera   +4 more
doaj  

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

Clinical, bio­chemical and genetic characteristics of familial forms of type 1 diabetes

Сахарный диабет
BACKGROUND: Familial clustering of type 1 diabetes (T1D) highlights the importance of genetic and environmental factors in the pathophysiology of diabetes mellitus (DM).
I. M. Zufarova, D. N. Laptev, I. R. Minniahmetov, R. I. Khusainova, S. V. Popov, E. V. Titovich, I. A. Eremina, V. A. Peterkova   +7 more
doaj   +1 more source

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

Advanced Science, EarlyView.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li, Yanjie Guo, Jianlin Li, Yimeng Li, Leqian Lin, Hoi Kit Matthew Leung, Qingqing Zhang, Kai‐Fai Lee, Ka‐Wang Cheung, Ernest H. Y. Ng, William S. B. Yeung, Philip C. N. Chiu, Cheuk‐Lun Lee   +12 more
wiley   +1 more source

CIITA-related block of HLA class II expression, upregulation of HLA class I, and heterogeneous expression of immune checkpoints in hepatocarcinomas: implications for new therapeutic approaches

OncoImmunology, 2019
Hepatocellular carcinoma (HCC) is the second cause of death for cancer worldwide, justifying the urgent need for novel therapeutic approaches. Immunotherapeutic strategies based on triggering and/or rescuing tumor antigen-specific T cells may be ...
Elise Ramia, Anna Maria Chiaravalli, Farah Bou Nasser Eddine, Alessandra Tedeschi, Fausto Sessa, Roberto S. Accolla, Greta Forlani   +6 more
doaj   +1 more source

Towards an HLA Run-time Infrastructure with Hard Real-time Capabilities [PDF]

, 2010
Our work takes place in the context of the HLA standard and its application in real-time systems context. The HLA standard is inadequate for taking into consideration the different constraints involved in real-time computer systems.
Adelantado, Martin, Chaudron, Jean-Baptiste, Siron, Pierre   +2 more
core  

Synthetic Malaria Peptide Vaccine Elicits High Levels of Antibodies in Vaccinees of Defined HLA Genotypes [PDF]

, 2000
Elizabeth Nardin, Giane A. Oliveira, J. Mauricio Calvo‐Calle, Z Castro, R S Nussenzweig, Barbara J. Schmeckpeper, Bradford Hall, Carter L. Diggs, Sacared A Bodison, Robert Edelman   +9 more
openalex   +1 more source

1034 Identification of a potentially novel regulatory axis involving KIR+CD8+ HLA-E/VL9 tetramer+ T cells and HLA-E^hi cTFH [PDF]

, 2023
Marcia Stickler, Tracey Chan, Seonhui Shim, Maria Pokrovskii, Kenneth Finn, Chirag H. Patel, Andrew Nguyen, Caitlin Connelly, Jonathan Powell, Fiona Harding   +9 more
openalex   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source