Results 21 to 30 of about 22,345 (254)

Neonates with acute liver failure have higher overall mortality but similar posttransplant outcomes as older infants

Liver Transplantation, EarlyView., 2022
Abstract Neonatal acute liver failure (ALF) carries a high mortality rate; however, little data exist on its peritransplant hospital course. This project aimed to identify factors associated with outcomes in neonates with ALF using large multicenter databases.
Swati Antala, Bridget Whitehead, Justin Godown, Matt Hall, Anna Banc‐Husu, Estella M. Alonso, Sarah A. Taylor   +6 more
wiley   +1 more source

HLH-26 is required for probiotic protection against S. enterica infection by regulating the canonical Wnt/BAR-1 pathway.

, 2022
(A) qRT-PCR validation of Wnt component genes (N = 3 biological replicates). Values are expressed as the fold difference compared with wild-type worms fed on E.
Yu Sang (2551267), Jie Ren (176083), Alejandro Aballay (51596)   +2 more
core   +1 more source

A retrospective survey of patients who discontinued participation in the JPLSG HLH-2004 clinical trial

, 2022
Although clinical trials have reported an improvement in the prognosis of hemophagocytic lymphohistiocytosis (HLH), current treatment outcomes are unsatisfactory, especially in severe cases.
坂本, 謙一, TAMURA, Akihiro, SAKAMOTO, Kenichi, 8875, 8996, 8997, 8873, KANEGANE, Hirokazu, 8874, DOI, Takehiko, 8995, SHIODA, Yoko, HASHIMOTO, Hiroya, 9000, YANAGISAWA, Ryu, 8998, 8877, 0000-0003-1499-538X, 8999, 30307532, NAKAZAWA, Yozo, ONO, Rintaro, ISHII, Eiichi   +22 more
core   +1 more source

Fulminant Familial Hemophagocytic Lymphohistiocytosis (FHL) in an infant masquerading septic shock - A case report

Journal of Pediatric Critical Care, 2016
Hemophagocytic lymphohistiocytosis (HLH) is a rare but life-threatening disease caused by uninhibited hyperinflammatory reaction that can lead to fulminant, life threatening multi organ failure and whose pathophysiology and clinical characteristics are ...
Rohit Kapoor, Prabhas Prasun Giri, Joydeep Das   +2 more
doaj   +1 more source

A Tribute to Franklin Shuler, MD, PhD, CIME (1967-2021)

Marshall Journal of Medicine, 2022
Dr. Franklin Shuler was a well-known Orthopaedic Surgeon amongst Marshall Health. He made breakthroughs in research, was a phenomenal mentor, and took care of his community and family. For 4 years, Dr.
Abigail Tolbert, Dipali Nemade
doaj   +1 more source

Immune checkpoint inhibitor-induced hemophagocytic lymphohistiocytosis in lung cancer: a case series [PDF]

Exploration of Targeted Anti-tumor Therapy
Immune checkpoint inhibitors (ICIs) are established treatments for various malignancies, including lung, kidney, and colorectal cancers. However, their broad use has led to an increase in immune-related adverse events (irAEs), with thyroiditis, colitis ...
Abdul Wali Khan, Simran Chandra, Himil Mahadevia, Janakiraman Subramanian, Ben Ponvilawan, Dhruv Bansal   +5 more
doaj   +1 more source

High Mortality of HLH in ICU Regardless Etiology or Treatment

Frontiers in Medicine, 2021
Background: Adult hemophagocytic lymphohistiocytosis (HLH) is highly lethal in the ICU. The diagnostic and therapeutic emergency that HLH represents is compounded by its unknown pathophysiological mechanisms.
Amandine Bichon, Amandine Bichon, Jérémy Bourenne, Jérémy Bourenne, Jérôme Allardet-Servent, Laurent Papazian, Laurent Papazian, Sami Hraiech, Sami Hraiech, Christophe Guervilly, Christophe Guervilly, Vanessa Pauly, Gilles Kaplanski, Gilles Kaplanski, Djamel Mokart, Marc Gainnier, Marc Gainnier, Julien Carvelli, Julien Carvelli   +18 more
doaj   +1 more source

HLH

, 2023
Comprehensive evaluation of immune dysregulation in secondary hemophagocytic lymphohistiocytosis.
Ting (17398711)
core   +1 more source

Cytophagic Histiocytic Panniculitis Presenting as Subcutaneous Nodules and Generalized Edema – A Case Report

Clinical, Cosmetic and Investigational Dermatology, 2023
Jiayi Yang,* Lihong Chen,* Ruofei Shi, Xiaoqing Zhao, Meng Pan, Jie Zheng Department of Dermatology, School of Medicine, Ruijin Hospital, Shanghai Jiao Tong University, Shanghai, People’s Republic of China*These authors contributed equally to
Yang J, Chen L, Shi R, Zhao X, Pan M, Zheng J   +5 more
doaj  

An uncommon diagnosis of a young female with fever of unknown origin (FUO): Idiopathic Hemophagocytic Lymphohistiocytosis (HLH) [PDF]

Romanian Journal of Rheumatology
Background. Hemophagocytic Lymphohistiocytosis (HLH), characterized by uncontrolled activation of immune cells leading to a hyperinflammatory state, is seldom considered in the initial differential diagnosis of FUO.
Amukthamalyada Koduri, Anuhya Adusumilli, Ramkumar Murali, Magesh Kumar S.   +3 more
doaj   +1 more source