Results 41 to 50 of about 22,345 (254)

Malignancy-induced hemophagocytic lymphohistiocytosis in a case of signet ring cell carcinoma of the stomach

open access: yesIndian Journal of Pathology and Microbiology, 2021
Hemophagocytic lymphohistiocytosis (HLH) is a rare and potentially life-threatening condition associated with high mortality and can be classified into primary (familial) and secondary HLH.
Subramaniam Ramkumar
doaj   +1 more source

HLH-1 is required for establishing muscle proteostasis.

open access: yes, 2016
(A) Q0, Q35, Q0;hlh-1(cc561) or Q35;hlh-1(cc561) embryos laid at 15°C were scored for embryonic arrest. Data are presented as means ± SEM of at least 6 independent experiments.
Yael Bar-Lavan (3608987)   +5 more
core   +1 more source

Dengue hemorhagic fever associated hemophagocytc lymphohistiocytosis in primigravida: A case report

open access: yesAsian Pacific Journal of Tropical Medicine
Rationale: Hemophagocytic lymphohistiocytosis (HLH) is a rare but severe complication of dengue virus infection, associated with high mortality. We report a case of a 9-week primigravida presenting with high grade fever spikes and a positive Dengue NS1 ...
Pyrus Bhellum   +3 more
doaj   +1 more source

Pathogenic Gene Mutations or Variants Identified by Targeted Gene Sequencing in Adults With Hemophagocytic Lymphohistiocytosis

open access: yesFrontiers in Immunology, 2019
Hemophagocytic lymphohistiocytosis (HLH) can be classified into primary HLH and secondary HLH. Primary HLH usually occurs in infants and children with an underlying genetic defect, and there are also teens and occasional adults with primary HLH.
Yi Miao   +47 more
doaj   +1 more source

Genetic features of late onset primary hemophagocytic lymphohistiocytosis in adolescence or adulthood. [PDF]

open access: yesPLoS ONE, 2014
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition of uncontrolled immune activation leading to extreme inflammation. Primary HLH was once believed to be a disease that occurred only in infancy or young children, and was rarely ...
Yini Wang   +9 more
doaj   +1 more source

HLH-30/TFEB regulates a complex transcriptional network critical for nutrient sensing and starvation defenses.

open access: yes, 2019
In wild-type C. elegans under starvation conditions, HLH-30 activates lysosome biogenesis and catabolic pathways, which encourage starvation survival and prime the animal for recovery from starvation upon re-feeding. Without HLH-30, C.
Ben Zhou (197219)   +1 more
core   +1 more source

IMPORTANCE OF HYPERBILURUBINEMIA IN DIFFERENTIATION OF PRIMARY AND SECONDARY HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS IN PEDIATRIC CASES

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2014
Background and objective: Hemophagocytic lymphohistiocytosis (HLH) is a life threatening hyper inflammatory disease. It is difficult to differentiate between primary and secondary HLH based on clinical findings at the onset of disease.
seval ozen   +7 more
doaj   +1 more source

Extreme hypertriglyceridemia in an infant with hemophagocytic lymphohistiocytosis and hydroxycobalamin deficiency [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2015
Introduction. Hemophagocytic lymphohistiocytosis (HLH) is a severe hyperinflammatory condition characterized by fever, cytopenias, hepatosplenomegaly and hemophagocytosis.
Dokmanović Lidija   +6 more
doaj   +1 more source

Case report: Ruxolitinib plus dexamethasone as first-line therapy in haemophagocytic lymphohistiocytosis

open access: yesFrontiers in Oncology, 2023
Haemophagocytic lymphohistiocytosis (HLH) is a cytokine-driven inflammatory syndrome caused by uncontrolled hypersecretion of inflammatory cytokines. Conventional first-line treatment for HLH included HLH-94 and HLH-2004 regimens.
Lin Zhao   +4 more
doaj   +1 more source

HLHS: Power of the Chick Model

open access: yesJournal of Cardiovascular Development and Disease, 2022
Background: Hypoplastic left heart syndrome (HLHS) is a rare but deadly form of human congenital heart disease, most likely of diverse etiologies. Hemodynamic alterations such as those resulting from premature foramen ovale closure or aortic stenosis are among the possible pathways.
openaire   +3 more sources

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