Results 131 to 140 of about 57,531 (234)
SCREENING OF HMG CO A REDUCTASE INHIBITOR PRODUCING MARINE ACTINOMYCETES [PDF]
, 2013 The objective of the present study was screening of 3-hydroxy-3- methyl glutaryl Co A (HMG CoA) reductase inhibitor producing marine actinomycetes.
SRILAKSHMI, SANKAR, PRABHAKAR,LAKSHMINARAYANA, SRINU, PHANI BHUSHAN,MOGES,
core +1 more source
Rethinking Statin Dosage in Coronary Disease
Pharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.It is widely acknowledged that a sufficient statin dose is important in the management of symptomatic coronary disease, along with weight reduction and appropriate antithrombotic, blood pressure, and diabetes pharmacotherapy. Mid‐range statin doses have been shown to achieve the maximum improvements in total mortality and have the advantage of greater ...
Simon B. Dimmitt +3 more
wiley +1 more source
Cholesterol metabolism. Its regulation at the hepatic and intestinal level [PDF]
, 1991 Aunque todas las células del organismo tienen capacidad para sintetizar colesterol, la mayor parte de la síntesis de éste, que da lugar a lo que se conoce como colesterol endógeno, se realiza en el hígado.
Molina, M.T. +2 more
core
Clinical and Translational Science, Volume 19, Issue 2, February 2026.ABSTRACT Intrinsic factors such as age and ethnicity influence statin pharmacokinetics (PK) and may increase the risk of muscle‐related adverse events. This study investigated the effect of age on the PK of simvastatin (SV) and its active metabolite, simvastatin acid (SVA), in healthy Thai subjects using an LC–MS/MS assay while accounting for key ...
Thanate Srimatimanon +11 more
wiley +1 more source
Insights Into circRNA‐Mediated Lipid Metabolism in Cancer Progression
Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.ABSTRACT Lipid metabolism reprogramming is one of the most prominent characteristics of cancer, but it is still unclear which regulatory pathways underlie this process in cancer cells. Circular RNAs (circRNAs) represent a novel category of non‐coding RNAs with multifaceted regulatory functions. While the biological roles of circRNAs in cancer have been
Zhiwei Miao +4 more
wiley +1 more source
Determination of 3-Hydroxy-3-methylglutaryl CoA Reductase Activity in Plants
The enzyme 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase catalyzes the NADPH-mediated reductive deacylation of HMG-CoA to mevalonic acid, which is the first committed step of the mevalonate pathway for isoprenoid biosynthesis.
Arró i Plans, Montserrat +3 more
core +1 more source
Predictive Modeling of HMG-CoA Reductase Inhibitory Activity and Design of New HMG-CoA Reductase Inhibitors. [PDF]
ACS Omega, 2023 Samizo S, Kaneko H.
europepmc +1 more source
Drug Design, Development and Therapy, 2015 Gunasekaran Baskaran,1 Shamala Salvamani,1 Siti Aqlima Ahmad,1 Noor Azmi Shaharuddin,1 Parveen Devi Pattiram,2 Mohd Yunus Shukor1 1Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences, 2Department of Food Technology ...
Baskaran G +5 more
doaj
HMG-CoA Reductase Inhibitors for Traumatic Brain Injury. [PDF]
Neurotherapeutics, 2023 Katlowitz K +3 more
europepmc +1 more source