Results 21 to 30 of about 71,842 (286)
HMGB1 in inflammation and cancer [PDF]
Journal of Hematology & Oncology, 2020 AbstractHigh mobility group box 1 (HMGB1) is a non-histone chromatin-associated protein widely distributed in eukaryotic cells and is involved in DNA damage repair and genomic stability maintenance. In response to stimulus like bacteria or chemoradiotherapy, HMGB1 can translocate to extracellular context as a danger alarmin, activate the immune ...
Shumin Wang, Yi Zhang
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Journal of Inflammation Research, 2022 Jie Bai,1– 3,* Bibo Wu,1– 3,* Shasha Zhao,1– 3,* Gang Wang,1– 3,* Shengfa Su,1– 3 Bing Lu,1– 3 Yinxiang Hu,1– 3 Yichao Geng,1,3 Zhengneng Guo,1– 3 Jun Wan,2,3 Weiwei OuYang,1– 3 Cheng Hu,1– 3 Jie Liu1– 3 1Department of Oncology, The ...
Bai J +12 more
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Clinical and Experimental Hypertension, 2023 Background Atherosclerosis has been recognized as a chronic inflammation initiated by dysfunction of endothelial cell that contributes to the increased morbidity and mortality of severe cardiovascular events.
Huai Yu, Hui Cao, Hang Yu
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Osmotic pressure: resisting or promoting DNA ejection from phage [PDF]
, 2008 Recent in vitro experiments have shown that DNA ejection from bacteriophage can be partially stopped by surrounding osmotic pressure when ejected DNA is digested by DNase I on the course of ejection.
Castelnovo, Martin +4 more
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Oxidative stress-mediated HMGB1 biology [PDF]
Frontiers in Physiology, 2015 High mobility group box 1 (HMGB1) is a widely-expressed and highly-abundant protein that acts as an extracellular signal upon active secretion by immune cells or passive release by dead, dying, and injured cells. Both intracellular and extracellular HMGB1 play pivotal roles in regulation of the cellular response to stress.
Yu, Yan, Tang, Daolin, Kang, Rui
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Neuropathic Pain in Rats with a Partial Sciatic Nerve Ligation Is Alleviated by Intravenous Injection of Monoclonal Antibody to High Mobility Group Box-1 [PDF]
, 2013 High mobility group box-1 (HMGB1) is associated with the pathogenesis of inflammatory diseases. A previous study reported that intravenous injection of anti-HMGB1 monoclonal antibody significantly attenuated brain edema in a rat model of stroke, possibly
D Lo Coco +43 more
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PUMA amplifies necroptosis signaling by activating cytosolic DNA sensors. [PDF]
, 2018 Necroptosis, a form of regulated necrotic cell death, is governed by RIP1/RIP3-mediated activation of MLKL. However, the signaling process leading to necroptotic death remains to be elucidated.
Chen, Dongshi +7 more
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HMGB1: Endogenous Danger Signaling
Molecular Medicine, 2008 While foreign pathogens and their products have long been known to activate the innate immune system, the recent recognition of a group of endogenous molecules that serve a similar function has provided a framework for understanding the overlap between the inflammatory responses activated by pathogens and injury.
Klune, John R +4 more
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How should novelty be valued in science? [PDF]
, 2014 Box plot analysis of serum concentrations of sRAGE (A), esRAGE (B), S100A9 (C) and HMGB1 (D) in patients with CTEPH (n = 26) and controls (n = 33). Independent Student’s t-test was used to compare groups. RAGE receptor for advanced glycation endproducts,
Ana-Iris Schiefer (547363) +13 more
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Cancer Management and Research, 2021 Yun Z, Meng F, Jiang P, Yue M, Li S. Cancer Manag Res. 2019;11:5821–5834. The Editor and Publisher of Cancer Management and Research wish to retract the published article.
Yun Z, Meng F, Jiang P, Yue M, Li S
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