Results 11 to 20 of about 42,486 (210)

Amino Acid Mutations in Hemagglutinin-Neuraminidase Enhance the Virulence and Pathogenicity of the Genotype III Newcastle Disease Vaccine Strain After Intravenous Inoculation

Frontiers in Veterinary Science, 2022
Newcastle disease virus (NDV), the causative agent that generally causes severe disease in poultry, continues to mutate and has thus evolved into 21 genotypes.
Xiaolong Lu, Xiaowen Liu, Xiaowen Liu, Qingqing Song, Xiaoquan Wang, Shunlin Hu, Xiufan Liu, Xiufan Liu, Xiufan Liu   +8 more
doaj   +1 more source

Hemagglutinin-neuraminidase Sequence and Phylogenetic Analysis of Two Newcastle Disease Virus Isolated from Chickens in Iran [PDF]

Archives of Razi Institute, 2021
Newcastle disease is a highly contagious viral infection affecting many species of birds that can spread fast between poultry houses and cause a heavy economic burden on the poultry industry all around the world.
M. H Kiani, M. H Bozorgmehrifard, H Hosseini, S Charkhkar, A Ghalyanchilangeroudi   +4 more
doaj   +1 more source

Humanin (HN) and glucose transporter 8 (GLUT8) in pregnancies complicated by intrauterine growth restriction. [PDF]

PLoS ONE, 2018
Intrauterine growth restriction (IUGR) results from a lack of nutrients transferred to the developing fetus, particularly oxygen and glucose. Increased expression of the cytoprotective mitochondrial peptide, humanin (HN), and the glucose transporter 8 ...
Carla Janzen, Margarida Y Y Lei, Il Seok D Jeong, Amit Ganguly, Peggy Sullivan, Vladislava Paharkova, Gina Capodanno, Hiromi Nakamura, Alix Perry, Bo-Chul Shin, Kuk-Wha Lee, Sherin U Devaskar   +11 more
doaj   +1 more source

Identification and characterization of hirudin-HN, a new thrombin inhibitor, from the salivary glands of Hirudo nipponia [PDF]

PeerJ, 2019
Transcriptome sequencing data (6.5 Gb) of the salivary glands of the haematophagous leech Hirudo nipponia was obtained by using the BGIseq-500 platform.
Boxing Cheng, Fei Liu, Qiaosheng Guo, Yuxi Lu, Hongzhuan Shi, Andong Ding, Chengfeng Xu   +6 more
doaj   +2 more sources

Molecular Characterization of Hemagglutinin-Neuraminidase Protein Virus Newcastle disease (ND) in Surabaya during 2003 and 2016

Jurnal Medik Veteriner, 2021
This study aimed to determine the mutation of amino acid, nucleotide homology, phylogenetic tree, epitope prediction of Hemagglutinin-Neuraminidase protein Newcastle Disease (ND) Virus isolated from traditional market around Surabaya.
Innah Wulandari, Jola Rahmahani, Indah Rahmawati, Nurvita Putih, Aisyah Azahro, Kusnoto Kusnoto, Rahayu Ernawati, Fedik Abdul Rantam   +7 more
doaj   +1 more source

Biological and Immunological Characterization of a Functional L-HN Derivative of Botulinum Neurotoxin Serotype F

Toxins, 2023
Botulinum neurotoxins (BoNTs) can cause nerve paralysis syndrome in mammals and other vertebrates. BoNTs are the most toxic biotoxins known and are classified as Class A biological warfare agents. BoNTs are mainly divided into seven serotypes A-G and new
Zhiying Li, Bolin Li, Jiansheng Lu, Xuyang Liu, Xiao Tan, Rong Wang, Peng Du, Shuo Yu, Qing Xu, Xiaobin Pang, Yunzhou Yu, Zhixin Yang   +11 more
doaj   +1 more source

Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) ectodomain. [PDF]

PLoS Pathogens, 2013
Paramyxoviruses cause a wide variety of human and animal diseases. They infect host cells using the coordinated action of two surface glycoproteins, the receptor binding protein (HN, H, or G) and the fusion protein (F). HN binds sialic acid on host cells
Brett D Welch, Ping Yuan, Sayantan Bose, Christopher A Kors, Robert A Lamb, Theodore S Jardetzky   +5 more
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The Molecular Structure and Role of Humanin in Neural and Skeletal Diseases, and in Tissue Regeneration

Frontiers in Cell and Developmental Biology, 2022
Humanin (HN) belongs to a member of mitochondrial-derived peptides (MDPs) which are encoded by mitochondrial genes. HN shares sequence homology with thirteen HN-like proteins, named MTRNR2L1 to MTRNR2L13, which encompass 24–28 amino acid residues in ...
Sipin Zhu, Xiaoyong Hu, Samuel Bennett, Jiake Xu, Yuliang Mai   +4 more
doaj   +1 more source

Hijacking the Fusion Complex of Human Parainfluenza Virus as an Antiviral Strategy

mBio, 2020
The receptor binding protein of parainfluenza virus, hemagglutinin-neuraminidase (HN), is responsible for actively triggering the viral fusion protein (F) to undergo a conformational change leading to insertion into the target cell and fusion of the ...
T. C. Marcink, E. Yariv, K. Rybkina, V. Más, F. T. Bovier, A. des Georges, A. L. Greninger, C. A. Alabi, M. Porotto, N. Ben-Tal, A. Moscona   +10 more
doaj   +1 more source

The Hemagglutinin-Neuraminidase (HN) Head Domain and the Fusion (F) Protein Stalk Domain of the Parainfluenza Viruses Affect the Specificity of the HN-F Interaction

Frontiers in Microbiology, 2018
Membrane fusion by the parainfluenza viruses is induced by virus-specific functional interaction between the attachment protein (HN) and the fusion (F) protein.
Masato Tsurudome, Junpei Ohtsuka, Morihiro Ito, Machiko Nishio, Tetsuya Nosaka   +4 more
doaj   +1 more source