Results 51 to 60 of about 41,460 (160)
Biophysical Studies Of The Hn-s Protein From Xyllela fastidiosa And Dna [PDF]
Biophysical Journal, 2009 The nucleoid-associated protein H-NS is a major component of the bacterial nucleoid, involved in DNA compaction and transcription regulation. Extensive studies on the biological functions demonstrated that H-NS plays a role in the regulation of many genes on the Escherichia coli chromosome, and represses the expression of a variety of proteins at the ...
Zeri, Ana-Carolina +5 more
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Chinese Journal of Lung Cancer, 2010 Background and objective Hemagglutinin-neuraminidase (HN) protein of newcastle disease virus is an important immunogen for oncolysis. We designed three different expression plasmids encoding the HN protein targeted to different subcellular compartments ...
Kaibing WANG +4 more
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Frontiers in Pharmacology, 2020 Considerable evidences have indicated that elevated uric acid (UA) was involved in renal tubular injury leading to hyperuricemic nephropathy (HN).
Guozheng Li +12 more
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The Translocation Domain of Botulinum Neurotoxin A Moderates the Propensity of the Catalytic Domain to Interact with Membranes at Acidic pH. [PDF]
PLoS ONE, 2016 Botulinum neurotoxin A (BoNT/A) is composed of three domains: a catalytic domain (LC), a translocation domain (HN) and a receptor-binding domain (HC). Like most bacterial toxins BoNT/A is an amphitropic protein, produced in a soluble form that is able to
Anne Araye +9 more
doaj +1 more source
Gasdermin D promotes hyperuricemia-induced renal tubular injury through RIG-I/caspase-1 pathway
iScience, 2023 Summary: Renal tubular epithelial cells injury is one of the most important pathological features in hyperuricemic nephropathy (HN). However, the involvement of gasdermin D (GSDMD)-mediated pyroptosis in HN remains obscure. We found GSDMD was upregulated
Lisha Ma +8 more
doaj +1 more source
Comprehensive Analysis and Characterization of Linear Antigenic Domains on HN Protein from Genotype VII Newcastle Disease Virus Using Yeast Surface Display System. [PDF]
PLoS ONE, 2015 Circulation of genotype VII Newcastle disease virus (NDV) has posed a great threat for the poultry industry worldwide. Antibodies against Hemagglutinin-neuraminidase (HN), a membrane protein of NDV with critical roles in NDV infection, have been reported
Tao Li +9 more
doaj +1 more source
Inhibition of Receptor Binding Stabilizes Newcastle Disease Virus HN and F Protein-Containing Complexes [PDF]
Journal of Virology, 2006 ABSTRACT Receptor binding of paramyxovirus attachment proteins and the interactions between attachment and fusion (F) proteins are thought to be central to activation of the F protein activity; however, mechanisms involved are unclear. To explore the relationships between Newcastle disease virus (NDV) HN and F protein interactions and HN ...
Cullen, Lori McGinnes +1 more
openaire +3 more sources
Frontiers in Microbiology, 2013 Human parainfluenza viruses (HPIVs) are the etiologic agents of lower respiratory infections and pneumonia in infants, young children and immunocompromised hosts.
Kyosuke eSenchi +4 more
doaj +1 more source
Potently neutralizing human mAbs against the zoonotic pararubulavirus Sosuga virus
JCI Insight, 2023 Sosuga virus (SOSV) is a recently discovered paramyxovirus with a single known human case of disease. There has been little laboratory research on SOSV pathogenesis or immunity, and no approved therapeutics or vaccines are available.
Helen M. Parrington +12 more
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Novel neutralizing human monoclonal antibodies against tetanus neurotoxin
Scientific Reports, 2021 Tetanus is a fatal disease caused by tetanus neurotoxin (TeNT). TeNT is composed of a light chain (Lc) and a heavy chain, the latter of which is classified into two domains, N-terminus Hn and C-terminus Hc.
Takeharu Minamitani +9 more
doaj +1 more source