Results 171 to 180 of about 32,692 (251)

Lysine l‐Lactylation: Bridging Metabolism, Chromatin and Disease

Cell Proliferation, Volume 59, Issue 8, August 2026.
Enzymatic regulation of KL‐la. The enzymatic regulation of KL‐la involves two distinct pathways for L‐lactate accumulation: intracellular production through glycolysis‐derived pyruvate conversion by lactate dehydrogenase (LDH) or direct cellular uptake via monocarboxylate transporters (MCTs). These L‐lactate pools fuel two distinct lactylation pathways—
Anoosha Malik, Muhammad Dilawar, Junguang Liao, Jie Zheng, Qitao Qian, Ming Xu, Sisi Lin, Xiaobo Zhu, Qiuwei Ge, Limin Jin, Guiqian Chen   +10 more
wiley   +1 more source

Editorial: Molecular mechanisms and therapeutic strategies of head and neck disease. [PDF]

Front Cell Dev Biol
Song YJ, Zhang X, Wang JH, Deng WW, Yang LL.   +4 more
europepmc   +1 more source

Mechanisms of Therapeutic Resistance and Recent Advances in Glioblastoma Treatment

Immunology &Cell Biology, Volume 104, Issue 7, Page 711-728, August 2026.
Three interconnected processes in glioblastoma (GBM) biology: initiation, stratification, and immunosuppression. 1) Initiation: GBM initiation is proposed to occur through migration of TERT mutation‐bearing neural stem cells from the subventricular zone to the frontal and temporal cortices, where a subsequent oncogenic transformation drives their ...
Emerson Achari, Farah Ahmady‐Nield, Amit Sharma, Ingo G. H. Schmidt‐Wolf, Jarek Maciaczyk, Rodney B. Luwor, Adrian A. Achuthan   +6 more
wiley   +1 more source

Radiosensitisation of Head and Neck Cancer Cells to Protons of Increasing LET Through Targeting DNA Double Strand Break Repair. [PDF]

Cells
Dufficy ER, Goula A, Melia E, Bellamy A, Parsons JL.   +4 more
europepmc   +1 more source

Machine Learning of Personal Repertoires From Public T Cell Receptors

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT The T‐cell receptor (TCR) repertoire records an individual's immunological history, but most unique CDR3 sequences in any one person are private and uninformative about anyone else. A small subset, however, recurs predictably across unrelated donors.
Or Malca, Alona Zilberberg, Sol Efroni
wiley   +1 more source

Real-world healthcare resource use and costs associated with the management of locally advanced head and neck cancer in Portugal - TRACE2 study. [PDF]

Front Oncol
Teixeira MM, Magalhães J, Marinho J, Ladeira K, Morais C, Nogueira M.   +5 more
europepmc   +1 more source

The Prognostic Significance of Tertiary Lymphoid Structures in Head and Neck Cancers: A Systematic Review and Meta‐Analysis

Journal of Oral Pathology &Medicine, Volume 55, Issue 7, Page 774-783, August 2026.
ABSTRACT Background Head and neck squamous cell carcinoma (HNSCC), particularly oral squamous cell carcinoma (OSCC), is associated with poor survival despite therapeutic advances. Tertiary lymphoid structures (TLSs) are emerging components of the tumor microenvironment, but their prognostic significance in HNSCC remains unclear.
Everton Freitas de Morais, Bruno Cesar da Costa, Antti Mäkitie, Ricardo D. Coletta, Alhadi Almangush   +4 more
wiley   +1 more source

LncRNA MIR4435-2HG-mediated succinylation of USF1 promotes its protein stability and induces epithelial-mesenchymal transition in HNSCC. [PDF]

Epigenetics
He S, Wang J, Wang D, Wang W, Han A, Liu H.   +5 more
europepmc   +1 more source

Integr(at)in(g) EGFR therapy in HNSCC.

Annals of translational medicine, 2015
D'AMATO, VALENTINA, ROSA, ROBERTA, BIANCO, ROBERTO   +2 more
openaire   +2 more sources

Advances in Immunotherapy for Head and Neck Squamous Cell Carcinoma: Focus on PD-1/PD-L1 Blockade and Beyond. [PDF]

Clin Med Insights Oncol
Le F, Jiang Y, Chen Y, Huang X, Ouyang Q, Lü S.   +5 more
europepmc   +1 more source