Results 111 to 120 of about 22,040,645 (295)

NRF2/HO-1 axis regulates fructose-induced lipid accumulation in hepatocytes

open access: yesRedox Experimental Medicine
Objective: Nuclear factor erythroid 2-related factor 2 (NRF2), a key transcription factor involved in redox homeostasis, plays a critical role in preventing lipid peroxidation against various hepatic disorders, including metabolic dysfunction-associated ...
Bengu Cetinkaya   +6 more
doaj   +1 more source

1,3,4, Oxadiazole Compound A3 Provides Robust Protection Against PTZ-Induced Neuroinflammation and Oxidative Stress by Regulating Nrf2-Pathway

open access: yesJournal of Inflammation Research, 2021
Arooj Mohsin Alvi,1,2 Fawad Ali Shah,2 Asmaa Jan Muhammad,2 Jinxing Feng,1 Shupeng Li3 1Department of Neonatology, Shenzhen Children’s Hospital Shenzhen, Shenzhen, People’s Republic of China; 2Department of Pharmacology, Riphah Institute of ...
Alvi AM   +4 more
doaj  

Ginsenoside Rb1 Attenuates Intestinal Ischemia Reperfusion Induced Renal Injury by Activating Nrf2/ARE Pathway

open access: yesMolecules, 2012
Intestinal ischemia reperfusion (IIR) is a serious clinical condition associated with simultaneous multiple organ dysfunction. The aim of this study was to investigate the effects of ginsenoside Rb1 on IIR induced renal injury in mice.
Zhong-Yuan Xia   +3 more
doaj   +1 more source

Novel compound heterozygous stop‐gain mutations of LRBA in a Vietnamese patient with Common Variable Immune Deficiency

open access: yesMolecular Genetics & Genomic Medicine, 2020
Background Lipopolysaccharide‐responsive and beige‐like anchor (LRBA) deficiency is a rare autosomal recessive common variable immunodeficiency (CVID), affecting 1:25,000–1:50,000 people worldwide.
Anh N. L. Phan   +7 more
doaj   +1 more source

Ironic Medications: A Narrative‐Based Psycho‐Educational Intervention to Explore Patient–Provider Communication in Adolescents With Haematological Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adolescents with haematological malignancies face significant emotional and relational challenges, often accompanied by difficulties in communicating their needs within the healthcare context. To address these issues, a narrative‐based psycho‐educational intervention based on the creation and prescription of Ironic Medications was ...
Marta Stoppa   +7 more
wiley   +1 more source

Incidence and Severity of Carboplatin‐Associated Hearing Loss in Children With Cancer Assessed by the SIOP Boston 2012 Ototoxicity Criteria

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Platinum‐based chemotherapy is known to cause severe and debilitating hearing loss, but unlike cisplatin, the true incidence of carboplatin‐induced hearing loss remains unclear. We evaluated functional hearing outcomes in children receiving carboplatin to determine the incidence and severity of ototoxicity. Procedure We identified a
Aniket Chawla   +6 more
wiley   +1 more source

The effectiveness of a thesis writing seminar for graduate students at Ho Chi Minh City Open University [PDF]

open access: yes, 2021
The purpose of this essay was to investigate whether the seminar was necessary and effective in terms of helping graduate students in TESOL program at Ho Chi Minh City Open University (HCMC OU) conduct their thesis.
Ho, Pham Vu Phi
core   +1 more source

Re‐Irradiation in Pediatric Diffuse Midline Glioma: A Multi‐Institutional Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with recurrent diffuse midline gliomas (DMGs) have limited therapeutic options at recurrence. Re‐irradiation (RT2) may be used at progression, but with uncertainty about the benefit. Methods We conducted a multi‐institutional retrospective study of children aged < 18 with DMG treated at three centers (Toronto, Canada ...
Ajay Thomas Alex   +13 more
wiley   +1 more source

Ho Ho Cafe [PDF]

open access: yes, 2016
Menu from Ho Ho Caf̩ restaurant in Ottawa, ON. Gung (soup), appetizers, yet ca mein (Chinese noodles), chop suey, chow fan (fried rice), tasty spareribs, won ton, chow mein, sea food treats, dan foo young, special full course dinners, fresh fish, guy and
Ho Ho Cafe
core  

Microglial HO‐1 induction by curcumin provides antioxidant, antineuroinflammatory, and glioprotective effects [PDF]

open access: yes, 2015
Scope: We have studied if curcumin can protect glial cells under an oxidative stress and inflammatory environment, which is known to be deleterious in neurodegeneration.
Javier Egea   +11 more
core   +1 more source

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