Results 121 to 130 of about 465,102 (291)

Heme oxygenase-1 induction in hepatocytes and non-parenchymal cells protects against liver injury during endotoxemia [PDF]

, 2004
INTRODUCTION:Heme oxygenase-1 (HO-1) is a stress response enzyme, which catalyses the breakdown of heme into biliverdin-IX alpha, carbon monoxide and ferrous iron.
Bajt, Mary, Dorman, Robert, Farhood, Anwar, Jaeschke, Hartmut, Mayes, January   +4 more
core   +2 more sources

Genotype–phenotype correlation and CRIM status in Vietnamese children with Pompe disease: a single-center experience

Future Science OA
Background Pompe disease (PD) is a rare autosomal recessive disorder caused by pathogenic variants in the GAA gene, resulting in deficient lysosomal acid α-glucosidase activity.
Thanh Huong Thi Nguyen, Ngoc Trang Thi Nguyen, Hong Phuong Thi Chu, Hong Nhung Thi Tran, Ngoc Mai Duong, Y-Thanh Lu, Hung Sang Tang, Diep Tuan Tran, Phung Nguyen The Nguyen   +8 more
doaj   +1 more source

Defining Roles in Pediatric Palliative Care: Perspectives From Oncology and Palliative Care Teams

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Early integration of pediatric palliative care (PPC) is associated with improved symptom management, quality of life, and healthcare utilization for children with cancer. Despite this, variation persists in how PPC is understood, operationalized, and integrated within pediatric oncology programs. In particular, ambiguity surrounding
Leeat Granek, Lori Wiener, Stephanie Veldhuijzen van Zanten, Donna Johnston, Fyeza Hasan, Adam Rapoport, Nathasha Datoo, Kimberley Widger, Sumit Gupta, Karen Fergus, Anthony K. C. Chan, Alisha Kassam, Emily McCullogh, Dave Lysecki   +13 more
wiley   +1 more source

Identification and characterization of [6]-shogaol from ginger as inhibitor of vascular smooth muscle cell proliferation [PDF]

, 2015
Scope Vascular smooth muscle cell (VSMC) proliferation is involved in the pathogenesis of cardiovascular disease, making the identification of new counteracting agents and their mechanisms of action relevant.
Andreas Schinkovitz, Atanas G. Atanasov, Barbara Gröblacher, Dean Guo, Elke H. Heiss, Franz Bucar, Nadine Sider, R. China, Rongxia Liu, Rudolf Bauer, Verena M. Dirsch   +10 more
core   +4 more sources

Apigenin-Loaded Solid Lipid Nanoparticle Attenuates Diabetic Nephropathy Induced by Streptozotocin Nicotinamide Through Nrf2/HO-1/NF-kB Signalling Pathway [Retraction]

International Journal of Nanomedicine, 2022
Li P, Bukhari SNA, Khan T, et al. Int J Nanomedicine. 2020;15:9115–9124. The Editor and Publisher of International Journal of Nanomedicine wish to retract the published article.
Li P, Bukhari SNA, Khan T, Chitti R, Bevoor DB, Hiremath AR, SreeHarsha N, Singh Y, Gubbiyappa KS   +8 more
doaj  

Feasibility and Preliminary Efficacy of Integrative Neuromuscular Training for Childhood Cancer Survivors: A Pilot Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian, Robert U. Newton, Dennis R. Taaffe, Nicholas G. Gottardo, Santosh Valvi, Carolyn J. Peddle‐McIntyre, Jodie Cochrane Wilkie, Daniel A. Galvão   +7 more
wiley   +1 more source

H-ferritin ferroxidase induces cytoprotective pathways and inhibits microvascular stasis in transgenic sickle mice [PDF]

, 2014
Hemolysis, oxidative stress, inflammation, vaso-occlusion and organ infarction are hallmarks of sickle cell disease (SCD). We have previously shown that increases in heme oxygenase-1 (HO-1) activity detoxify heme and inhibit vaso-occlusion in transgenic ...
Carol M. Bruzzone, Chunsheng Chen, Clifford J. Steer, Fatima B. Khan, Graham Brown, Gregory M. Vercellotti, Heather Bechtel, John D. Belcher, Julia Nguyen, Karl A. Nath, Robert P. Hebbel   +10 more
core   +2 more sources

Protective role of H2S on acute renal damages in urinary-derived sepsis

Biotechnology & Biotechnological Equipment, 2019
The aim of this study was to investigate the protective roles of H2S on acute renal damage in urinary-derived sepsis. Totally 40 male rabbits were randomly divided into the Control, Sham, Sepsis, NaHS and the dl-propargylglycine (PAG) groups. White blood
Wujun Xu, Yachun Tang, Xiaofeng Zhao, Liwen Zhao, Xiaobin Wu, Li Liu, Xiangyang Long, Zhigang Luo, Xian Chen, Binhui Wang   +9 more
doaj   +1 more source

The Role of Invasive Procedures in the Treatment of Complicated Gastrointestinal Graft‐Versus‐Host Disease in Pediatric Patients

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti, Giorgio Persano, Chiara Grimaldi, Pier Luigi Di Paolo, Carmen Malaspina, Francesco Quagliarella, Valerio Balassone, Anna Chiara Iolanda Contini, Gian Luigi Natali, Rita Alaggio, Ivan Pietro Aloi, Tamara Caldaro, Alessandro Crocoli   +12 more
wiley   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider, Amelie Alfert, Marc Hotfilder, Birgit Burkardt, Marcel te Vrugt   +4 more
wiley   +1 more source