HO-1 Protects against Hypoxia/Reoxygenation-Induced Mitochondrial Dysfunction in H9c2 Cardiomyocytes. [PDF]
BACKGROUND:Mitochondrial dysfunction would ultimately lead to myocardial cell apoptosis and death during ischemia-reperfusion injuries. Autophagy could ameliorate mitochondrial dysfunction by autophagosome forming, which is a catabolic process to ...
Zhe Jin +17 more
core +1 more source
Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge +6 more
wiley +1 more source
ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita +5 more
wiley +1 more source
Qiongphasma bispinosum subsp. bispinosum Ho 2013 [PDF]
Qiongphasma bispinosum bispinosum Ho, 2013 E/T Qiongphasma bispinosus bispinosus, Ho, 2013d: 415, figs. 14–15, 24, 26, 28–29, 38–39. Types. Holotype: ♂, Diaoluoshan National Nature Reserve, Lingshui, Hainan, China, 6.VII.2011, George Ho Wai ...
Ho, George Wai-Chun
core +1 more source
Early Impact of Childhood Opportunity on Neurocognitive Outcomes in Sickle Cell Disease
ABSTRACT Introduction Neurocognitive impairment is a well‐recognized complication of sickle cell disease (SCD) that begins early in childhood and persists across development. While cerebrovascular injury contributes substantially to risk, neurocognitive deficits are also observed in children without overt or silent cerebral infarctions, suggesting ...
Julia E. LaMotte +5 more
wiley +1 more source
HO-1 deficiency does not affect IL-6-mediated signaling to hepcidin in primary murine hepatocytes. [PDF]
Primary hepatocytes were isolated from livers of Hmox1Alb-Cre and Hmox1fl/fl mice. The cells were cultured in serum-free media and treated with 20 ng/ml murine IL-6.
Edouard Charlebois (6945308) +2 more
core +1 more source
Total flavonoids of Selaginella tamariscina (P. Beauv.) Spring ameliorates diabetes-induced acute lung injury via activating Nrf2/ HO-1 [PDF]
Objective(s): This investigation explored the mechanism by which the total flavonoids of Selaginella tamariscina (P.Beauv.) Spring (TFST) mitigate oxidative stress through the activation of the heme oxygenase-1 (HO-1) signaling pathway mediated by ...
Lina Chen +4 more
doaj +1 more source
The role of Nrf2 in astragaloside IV-mediated antioxidative protection on heart failure
Context Heart failure is one of the most serious diseases worldwide. Astragaloside IV (ASI) is widely used in the treatment of cardiovascular diseases.
Yan-Bo Sui +4 more
doaj +1 more source
ABSTRACT Background Pediatric bone sarcoma patients and survivors may experience psychosocial challenges related to childhood cancer after their intensive, body‐altering treatment. This cross‐sectional study aimed to evaluate generic and survivor‐specific psychosocial outcomes in a national cohort of pediatric bone sarcoma patients and survivors, and ...
Hinke van der Hoek +14 more
wiley +1 more source
Camellia sinensis with its active compound EGCG can decrease necroptosis via inhibition of HO-1 expression [PDF]
Stroke is the most common neurological disorder in the word. During ischemic stroke there is increasing of oxidative stress. Green tea (Camellia sinensis) have antioxidant and free radical scavenger effect. In vivo study using male Rattus Novergicus with
Imam Susilo +9 more
core

