Results 171 to 180 of about 99,018 (274)

Orchestrating the metastatic symphony: the role of extracellular vesicles in the epithelial–mesenchymal transition and pulmonary niche formation of breast cancer

open access: yesBiological Reviews, Volume 101, Issue 5, Page 2103-2118, October 2026.
ABSTRACT The complexity of breast cancer (BC) lung metastasis lies in the capacity of tumour cells to interact efficiently with distant organs to promote colonisation, a process that involves the sophisticated coordination of inherent cellular plasticity and the remodelling of the distant microenvironment.
Jian Lu   +12 more
wiley   +1 more source

CCNE1: A Cell Cycle Regulator That Influences Tumor Progression

open access: yesCancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACTCyclin E1 (CCNE1), a pivotal member of the cyclin family, governs the G1/S phase transition of the cell cycle by binding to and activating cyclin‐dependent kinase 2 (CDK2), thereby initiating DNA replication and driving S‐phase entry. In a broad spectrum of human malignancies—including breast, ovarian, gastric, and non‐small cell lung cancers ...
Liang Yan   +6 more
wiley   +1 more source

Patterns of Proliferation in the Pacific Hagfish (Eptatretus stoutii) Retina Suggest an Ancient Origin for Adult Neurogenesis

open access: yesJournal of Comparative Neurology, Volume 534, Issue 10, October 2026.
The hagfish, a jawless early‐branching vertebrate, has very rudimentary eyes that are diminutive and oddly devoid of melanin pigment. Yet, the degenerate hagfish eye grows throughout life and expresses canonical genes of vertebrate retinal development. ABSTRACT Comparative morphology has revealed fascinating structural and organizational differences in
Sarah N. Bradshaw, William T. Allison
wiley   +1 more source

Prognostic value and potential upstream regulator of Schwann cells in esophageal squamous cell carcinoma. [PDF]

open access: yesTransl Cancer Res
Lei Y   +9 more
europepmc   +1 more source

Posttranslational Modifications of p62/SQSTM1 in Health and Disease

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Schematic illustration of p62 as a posttranslational modifications (PTMs)‐programmed integrator in homeostasis, pathogenesis, and therapeutic targeting. (Left) Homeostasis: In physiological states, p62, through various PTMs such as phosphorylation, ubiquitination, and acetylation, coordinates essential cellular functions.
Weikai Wang   +8 more
wiley   +1 more source

Organoids: Current Applications and Future Directions

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Organoids are three‐dimensional multicellular structures derived from stem cells or primary tissues that recapitulate key structural and functional features of native organs. Advances in stem cell biology, biomaterials, and bioengineering have established organoids as powerful platforms for studying human development and disease mechanisms, drug ...
Yueqi Leng   +14 more
wiley   +1 more source

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