Functional roles and clinical implications of pseudogenes signatures as emerging biomarkers in cancer. [PDF]
Zaki MB +8 more
europepmc +1 more source
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley +1 more source
Transcriptome profiling of ocular surface ectoderm derived from embryonic stem cells, and identification of CACNG6 and AQP3 as its surface markers. [PDF]
Sun L +10 more
europepmc +1 more source
Intratumoral Microbiota in Fueling Cancer and Steering Treatment Response
Emerging research underscores the tumor‐specific colonization of microbiota and the role of intratumoral microbiota in cancer development and treatment resistance across multiple malignancies. Here, we provide a systematic review exploring the latest biotechnological advancements for studying low‐abundance intratumoral microbiota, their origins ...
Minhui Xu +7 more
wiley +1 more source
Harnessing Endogenous Homeobox Genes for Synthetic Apomixis in Hybrid Rice. [PDF]
Wei X +7 more
europepmc +1 more source
Role of Extracellular Vesicles in Shaping Immune Responses in the Lymph Node Microenvironment
Functional alliances of stromal, innate and adaptive immune cells in EV immunity in the lymph node. EV reflect the phenotype of their mother cell and cluster material from their surroundings. In the lymph node, EV preserve valuable context information between multiple cellular effectors to coordinate immunity in adaption to change.
Alicia Charrier +4 more
wiley +1 more source
Excreting the stress: a novel regulatory cascade drives salt gland development in Limonium bicolor. [PDF]
Wang G.
europepmc +1 more source
ABSTRACT Predicting population, species, and community responses to climate change is critical for the successful management of wild ecosystems. However, climate change does not act alone. Interactions among climate change and other anthropogenic threats could significantly complicate predictions of global change yet have rarely been examined.
Hallie Arno +7 more
wiley +1 more source
Non-coding regulatory variants in adolescent idiopathic scoliosis risk and pathogenesis. [PDF]
Ramkhalawan D, Parrales P, Makki N.
europepmc +1 more source
Genetic Monitoring of Tibial Hemimelia in Galloway Cattle
Animal Genetics, Volume 57, Issue 5, October 2026.
Bertram Brenig
wiley +1 more source

