Results 11 to 20 of about 45,307 (198)
Expression and Purification of Homeodomain [PDF]
Journal of Sciences, Islamic Republic of Iran, 2009 Homeobox genes encode transcription factors which play important roles in the developmental processes of many multicellular organisms. TGIFLX/Y (TGIFLX and TGIFLY) are members of the homeobox superfamily of genes.
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Evolutionary Classification of Homeodomains [PDF]
Journal of Assisted Reproduction and Genetics, 1998 We performed multiple comparisons between available amino acid (aa) sequences of homeodomain(HOM)-containing proteins from a wide spectrum of animals to create an evolutionary classification of the proteins.Based on results of statistical and special computational analyses of over 500 homeodomain aa sequences (HOMs) a novel system of concepts ...
V, Gindilis, E, Goltsman, Y, Verlinsky
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Homeodomain proteins: an update [PDF]
Chromosoma, 2015 Here, we provide an update of our review on homeobox genes that we wrote together with Walter Gehring in 1994. Since then, comprehensive surveys of homeobox genes have become possible due to genome sequencing projects. Using the 103 Drosophila homeobox genes as example, we present an updated classification. In animals, there are 16 major classes, ANTP,
Bürglin, Thomas R., Affolter, Markus
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The Gtx Homeodomain Transcription Factor Exerts Neuroprotection Using Its Homeodomain [PDF]
Journal of Biological Chemistry, 2004 Certain cases of familial Alzheimer's disease are caused by mutants of amyloid-beta precursor protein (AbetaPP), including V642I-AbetaPP, K595N/M596L-AbetaPP (NL-AbetaPP), A617G-AbetaPP, and L648P-AbetaPP. By using an unbiased functional screening with transfection and expression of a human brain cDNA library, we searched for genes that protect ...
Yuichi, Hashimoto +6 more
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The DUX4 homeodomains mediate inhibition of myogenesis and are functionally exchangeable with the Pax7 homeodomain [PDF]
Journal of Cell Science, 2017 ABSTRACT Facioscapulohumeral muscular dystrophy (FSHD) is caused by inappropriate expression of the double homeodomain protein DUX4. DUX4 has bimodal effects, inhibiting myogenic differentiation and blocking MyoD at low levels of expression, and killing myoblasts at high levels.
Darko Bosnakovski +8 more
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Hydration and DNA Recognition by Homeodomains [PDF]
Cell, 1996 A 2-nanosecond molecular dynamics (MD) simulation of an Antennapedia homeodomain-DNA complex in explicit solvent water at ambient temperature and pressure was performed to supplement experimental nuclear magnetic resonance (NMR) data on the structure and dynamics of this complex.
Billeter, Martin +3 more
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Molecular Analysis of the HOXA2-Dependent Degradation of RCHY1. [PDF]
PLoS ONE, 2015 The homeodomain transcription factor Hoxa2 interacts with the RING-finger type E3 ubiquitin ligase RCHY1 and induces its proteasomal degradation. In this work, we dissected this non-transcriptional activity of Hoxa2 at the molecular level.
Laure Bridoux +3 more
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The Colletotrichum lagenarium Ste12-Like Gene CST1 Is Essential for Appressorium Penetration
Molecular Plant-Microbe Interactions, 2003 Colletotrichum lagenarium is the causal agent of anthracnose of cucumber. This fungus produces a darkly melanized infection structure, appressoria, to penetrate the host leaves. The C.
Gento Tsuji +4 more
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The Homeodomain Resource: 2003 update [PDF]
Nucleic Acids Research, 2003 The Homeodomain Resource is a searchable, curated collection of information for the homeodomain protein family. The resource is organized in a compact form and provides user-friendly interfaces for both querying the component databases and assembling customized datasets.
Sharmila Banerjee-Basu +4 more
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A Lexicon for Homeodomain-DNA Recognition [PDF]
Cell, 2008 Decoding the cis-regulatory logic of eukaryotic genomes requires knowledge of the DNA-binding specificities of all transcription factors. New work (Berger et al., 2008; Noyes et al., 2008) provides individual specificities for nearly all Drosophila and mouse homeodomains, key DNA-binding domains in many transcription factors.
Affolter, M., Slattery, M., Mann, R. S.
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