Results 21 to 30 of about 45,307 (198)
Structural studies of the engrailed homeodomain [PDF]
Protein Science, 1994 AbstractThe structure of the Drosophila engrailed homeodomain has been solved by molecular replacement and refined to an R‐factor of 19.7% at a resolution of 2.1 Å. This structure offers a high‐resolution view of an important family of DNA‐binding proteins and allows comparison to the structure of the same protein bound to DNA.
N D, Clarke +4 more
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Molecular Systems Biology, 2022 The correct wiring of neuronal circuits is one of the most complex processes in development, since axons form highly specific connections out of a vast number of possibilities. Circuit structure is genetically determined in vertebrates and invertebrates,
Jessica Velten +8 more
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Scientific Reports, 2023 HMX3 is a homeodomain protein with essential roles in CNS and ear development. Homeodomains are DNA-binding domains and hence homeodomain-containing proteins are usually assumed to be transcription factors.
William Haws +6 more
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Homeodomain Proteins: Cooperating to be different [PDF]
Current Biology, 1995 The product of the Drosophila extradenticle gene interacts cooperatively with homeodomain proteins encoded by homeotic selector genes, and may account in part for their distinct regulatory properties.
Wilson, David S., Desplan, Claude
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Homeodomain proteins hierarchically specify neuronal diversity and synaptic connectivity
eLifeHow our brain generates diverse neuron types that assemble into precise neural circuits remains unclear. Using Drosophila lamina neuron types (L1-L5), we show that the primary homeodomain transcription factor (HDTF) brain-specific homeobox (Bsh) is ...
Chundi Xu +4 more
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Journal of Developmental Biology, 2016 The silk gland of the silkworm Bombyx mori is a long tubular organ that is divided into several subparts along its anteroposterior (AP) axis. As a trait of terminal differentiation of the silk gland, several silk protein genes are expressed with unique ...
Shigeharu Takiya +2 more
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Current Opinion in Structural Biology, 1996 Homeodomain proteins play key roles in development and gene regulation in eukaryotes. Past structural studies have focused on the binding of monomeric homeodomains to DNA, but two recent structures have revealed how homeodomains bind DNA as multimers.
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G3: Genes, Genomes, Genetics, 2016 The initiation of sexual development in the important edible and medicinal mushroom Flammulina velutipes is controlled by special genes at two different, independent, mating type (MAT) loci: HD and PR. We expanded our understanding of the F.
Wei Wang +11 more
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A class I odorant receptor enhancer shares a functional motif with class II enhancers
Scientific Reports, 2021 In the mouse, 129 functional class I odorant receptor (OR) genes reside in a ~ 3 megabase huge gene cluster on chromosome 7. The J element, a long-range cis-regulatory element governs the singular expression of class I OR genes by exerting its effect ...
Tetsuo Iwata +2 more
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Effect of a Mating Type Gene Editing in Lentinula edodes Using RNP/Nanoparticle Complex
Journal of FungiGene editing using CRISPR/Cas9 is an innovative tool for developing new mushroom strains, offering a promising alternative to traditional breeding methods that are time-consuming and labor-intensive.
Minseek Kim +6 more
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