Results 51 to 60 of about 2,687,981 (207)

A Chemical Probe for Increasing Leaf Tocopherol Levels by Coordinated Modulation of Biosynthesis, Competition and Storage

open access: yesPlant Biotechnology Journal, Volume 24, Issue 4, Page 2204-2219, April 2026.
ABSTRACT Plant biofortification with phytonutrients typically relies on metabolic engineering strategies known as ‘push’ (enhancing biosynthetic flux), ‘block’ (inhibiting competing pathways) and ‘pull’ (promoting metabolite storage). Here, we describe a novel synthetic compound, X57, that simultaneously targets biosynthesis, competition and storage to
Pablo Perez‐Colao   +4 more
wiley   +1 more source

Studies on the oxidative polymerization of homogentisic acid to form pyomelanin.

open access: yes, 2021
The accumulation of homogentisic acid (HGA) in patients with alkaptonuria is associated with the concomitant deposition of pigments contain significant amounts of polymerised HGA (polyHGA) in the bodily tissues of the patients.
Galeb, Hanaa, Hardy, John
core   +2 more sources

Comparative Analysis of Fungal Communities and the Key “Golden‐Flower” Fungi in Fu Brick Tea From Seven Chinese Regions and Their Effects on the Quality of Summer‐Autumn Tea

open access: yesFood Frontiers, Volume 7, Issue 2, March 2026.
This study systematically investigated 52 Fu brick tea (FBT) samples collected from seven representative regions in China. High‐through put sequencing revealed that Aspergillus, Wallemia, and Candida were the predominant fungal genera across the samples.
Lisha Ran   +9 more
wiley   +1 more source

Antibacterial Activity of Gentisyl Alcohol and Homogentisic Acid

open access: yesExperimental Biology and Medicine, 1948
SummaryGentisyl alcohol in our experiments was found to have only slight antibacterial activity over a broad pH range. Our results with this compound are at variance with those of Brack1 but are in agreement with the original report of Raistrick and coworkers.5Homogentisic acid was found to have a definite but slight antibacterial activity.The effect ...
L D, ABBOTT, J D, SMITH, J D, REID
openaire   +2 more sources

Nutritional Composition, Phenolic Constituents, and Antioxidant Activity of the Edible Desert Truffle Terfezia claveryi (Chatin)

open access: yesJournal of Food Biochemistry, Volume 2026, Issue 1, 2026.
The edible desert truffle, Terfezia claveryi, is a highly valued wild macrofungal species native to the semiarid regions of Central Anatolia. This study provides molecular identification and a comprehensive biochemical evaluation of T. claveryi, using lyophilized material to assess its nutritional composition, phenolic profile, and antioxidant ...
Onur Bulut   +3 more
wiley   +1 more source

Serum concentrations and urinary excretion of homogentisic acid and tyrosine in normal subjects

open access: yes, 2014
Alkaptonuria (AKU) is a rare, inherited metabolic disease of tyrosine metabolism. Degradation of tyrosine is blocked at the level of homogentisic acid (HGA) due to a congenital lack of the enzyme homogentisate 1,2-dioxygenase.
Hughes, AT   +4 more
core   +3 more sources

Elicitation and precursor induced approaches for the enhancement of α−tocopherol production using suspension cultures of Solanum lycopersicum

open access: yesCurrent Plant Biology
Elicitation and precursor feeding are the effective strategies for enhancing the synthesis of bioactive compounds in plant cell suspension cultures. The present study aimed to explore an efficient elicitation and precursor feeding protocol and its effect
Harish Mani Chandra   +3 more
doaj   +1 more source

Assessment of genetically modified soybean GMB151 × DAS‐44406‐6 (application GMFF‐2024‐21774, EFSA‐Q‐2024‐00330)

open access: yesEFSA Journal, Volume 24, Issue 1, January 2026.
Abstract Genetically modified soybean GMB151 × DAS‐44406‐6 was developed by crossing to combine two single events: GMB151 and DAS‐44406‐6. The two‐event stack soybean expresses the Cry14Ab‐1, HPPD‐4, PAT, AAD‐12 and 2mEPSPS proteins to confer herbicide tolerance and resistance to plant parasitic nematodes.
EFSA Panel on Genetically Modified Organisms (GMO)   +28 more
wiley   +1 more source

Biosynthesis of H2S and Siderophores Targeting Gram‐Negative Bacterial Resistance to Reactive Oxygen Species

open access: yesAdvanced Science, Volume 12, Issue 45, December 4, 2025.
Discover how Gram‐negative bacteria develop resistance to reactive oxygen species, and how scientists aim to overcome this challenge. Abstract Reactive oxygen species (ROS) are a promising alternative bactericide. However, it is questioned that bacteria can potentially develop resistance to ROS, similar to their resistance against antibiotics and ...
Congyang Mao   +9 more
wiley   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +31 more
wiley   +1 more source

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