Results 61 to 70 of about 5,440 (220)

Urinary Homogentisic Acid: Determination by Thin-Layer Chromatography

open access: yesClinical Chemistry, 1973
Abstract A new method is described for qualitative and quantitative determination of urinary homogentisic acid. The method involves extraction of urine with ethyl acetate, thin-layer chromatography of the extract on Silica Gel G, elution of the homogentisic acid into water, and color development with Folin’s phenol reagent. Absorbance is
J M, Feldman, J, Bowman
openaire   +2 more sources

The Concise Guide to PHARMACOLOGY 2025/26: Enzymes

open access: yesBritish Journal of Pharmacology, Volume 182, Issue S1, Page S307-S403, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander   +31 more
wiley   +1 more source

Tyrosine metabolism of an acatalasemic patient and of the toxohor-mone treated mice [PDF]

open access: yes, 1957
Tyrosine metabolism of toxohormone-treated mice and acatalasemic patient was not disturbed. These facts do not concur with the report of Zannoni and Bert who stated that catalase was an essential factor for the oxidation of p-hydroxyphenylpyruvic acid.
Doi, Genjiro   +3 more
core   +1 more source

The Discovery of the Mode of Action of Nitisinone

open access: yesMetabolites, 2022
This review briefly discusses the discovery of the mode of action of the triketone herbicide, 2-(2-nitro-4-trifluormethylbenzoyl)-1,3-cyclohexanedione and its use as a drug Nitisinone for the treatment of inborn errors of tyrosine metabolism.
Edward A. Lock
doaj   +1 more source

Metabolic origins and transport of vitamin e biosynthetic precursors [PDF]

open access: yes, 2017
Tocochromanols are organic compounds mostly produced by photosynthetic organisms that exhibit vitamin E activity in animals. They result from the condensation of homogentisate with four different polyprenyl side chains derived all from geranylgeranyl ...
Mène-Saffrané, Laurent   +1 more
core   +2 more sources

Potential Distribution Prediction and Metabolite Analysis of Clematis tangutica(Maxim.) Korsh. On the Qinghai Plateau

open access: yesEcology and Evolution, Volume 15, Issue 10, October 2025.
This study provides a comprehensive analysis of Clematis tangutica's habitat distribution and metabolite composition under varying environmental conditions. The MaxEnt model identified UV‐B seasonality and elevation as the primary factors shaping its distribution, with the most suitable habitats concentrated in central and eastern Qinghai.
Haiwang Zhang   +5 more
wiley   +1 more source

Elicitation and precursor induced approaches for the enhancement of α−tocopherol production using suspension cultures of Solanum lycopersicum

open access: yesCurrent Plant Biology
Elicitation and precursor feeding are the effective strategies for enhancing the synthesis of bioactive compounds in plant cell suspension cultures. The present study aimed to explore an efficient elicitation and precursor feeding protocol and its effect
Harish Mani Chandra   +3 more
doaj   +1 more source

Comparing the Phenylalanine/Tyrosine Pathway and Related Factors between Keratopathy and No-Keratopathy Groups as Well as between Genders in Alkaptonuria during Nitisinone Treatment

open access: yesMetabolites, 2022
Nitisinone (NIT) causes tyrosinaemia and corneal keratopathy (KP), especially in men. However, the adaptation within the phenylalanine (PHE)/tyrosine (TYR) catabolic pathway during KP is not understood.
Lakshminarayan R. Ranganath   +10 more
doaj   +1 more source

The formation of homogentisate in the biosynthesis of tocopherol and plastoquinone in spinach chloroplasts [PDF]

open access: yes, 1982
Homogentisate is the precursor in the biosynthesis of -tocopherol and plastoquinone-9 in chloroplasts. It is formed of 4-hydroxyphenylpyruvate of the shikimate pathway by the 4-hydroxyphenylpyruvate dioxygenase.
B. Buchholz   +27 more
core   +1 more source

Bioactivity-guided purification of novel herbal antioxidant and anti-NO compounds from Euonymus laxiflorus Champ [PDF]

open access: yes, 2018
[[abstract]]Euonymus laxiflorus Champ., a medicinal herb collected in Vietnam, has been reported to show several potent bioactivities, including anti-NO, enzyme inhibition, hypoglycemic and antidiabetic effects.
Anh Dzung Nguyen   +7 more
core   +1 more source

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