THE ENZYMATIC CONVERSION OF HOMOGENTISIC ACID TO 4-FUMARYLACETOACETIC ACID
R G, RAVDIN, D I, CRANDALL
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Absorbance measurements of oxidation of homogentisic acid accelerated by the addition of alkaline solution with sodium hypochlorite pentahydrate. [PDF]
Tokuhara Y +10 more
europepmc +1 more source
The preparation of homogentisic acid and of 2:5-dihydroxyphenylethylamine [PDF]
G, Leaf, A, Neuberger
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The uniformity of the homogentisic acid excretion in alkaptonuria
A E, Garrod, T S, Hele
openaire +3 more sources
Reaction of quinone of homogentisic acid with biological amines [PDF]
R, Stoner, B B, Blivaiss
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Secondary osteoarthritis due to alkaptonuria: a case report [PDF]
Background & Aims: Alkaptonuria is a rare autosomal recessive genetic disorder caused by a deficiency of homogentisate 1,2-dioxygenase, leading to the accumulation of homogentisic acid.
Sabina Lois +4 more
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Conditional targeting in mice reveals that hepatic homogentisate 1,2-dioxygenase activity is essential in reducing circulating homogentisic acid and for effective therapy in the genetic disease alkaptonuria. [PDF]
Hughes JH +12 more
europepmc +1 more source
Shikimate crosstalk enables record-level homogentisic acid production in <i>Yarrowia lipolytica</i>. [PDF]
Xu C +6 more
europepmc +1 more source
Specific knockout of kidney homogentisate 1,2-dioxygenase reveals that local metabolism of tyrosine and homogentisic acid is negligible in alkaptonuria. [PDF]
Rutland DA +8 more
europepmc +1 more source

