Results 81 to 90 of about 2,687,981 (207)

Ochronotic Arthropathy of the Shoulder – A Rare Case Report

Journal of Orthopaedic Case Reports
Introduction: Alkaptonuria is a metabolic disorder due to accumulation of homogentisic acid, leading to destruction of major joints. Very few cases of ochronosis with shoulder involvement have been reported in literature. Case Report: We report a 31-year-
Ayyappan V Nair, Kiran V, Aravind Rajan, Bharath Bharadwaj MS, Manisha Ashwin Daware, Prince Shanavas Khan   +5 more
doaj   +1 more source

Detection of homogentisic acid by electrospray ionization mass spectrometry. [PDF]

J Clin Lab Anal, 2023
Tokuhara Y, Ohara K, Morinishi T, Yamaguchi K, Tada S.   +4 more
europepmc   +1 more source

Determination of homogentisic acid using HPLC with amperometric detection at carbon paste electrodes [PDF]

, 2017
Homogentisic acid is an intermediate of the metabolic breakdown of tyrosine and phenylalanine; its accumulation in body fluids suggests the break in the metabolic pathway of these compounds and related health-threatening complications.
Lozano Alonso, María
core  

Ease of sutureless aortic valve replacement in a patient with unexpected ochronosis: a case report

Journal of Cardiothoracic Surgery
Background Alkaptonuria is a rare congenital metabolic disorder characterized by homogentisic acid accumulation in body cartilage and connective tissues due to a deficient homogentisic acid dioxygenase enzyme.
Saeid Hosseini, Soheila Salari, Mohammad Javad Alemzadeh Ansari, Mahshid Hesami, Sepideh Banar, Mohammad Amin Shojaei   +5 more
doaj   +1 more source

Aortic stenosis and coronary artery disease caused by alkaptonuria, a rare genetic metabolic syndrome

, 1998
Alkaptonuria is a rare metabolic disease in which homogentisic acid deposits occur in various body tissues. We present a case of alkaptonuria which resulted in aortic stenosis and coronary artery disease due to homogentisic acid ...
Vavuranakis, M, Stefanadis, C, Toutouzas, P, Triantafillidi, H   +3 more
core  

Discovery of Homogentisic Acid as a Precursor in Trimethoprim Metabolism and Natural Product Biosynthesis. [PDF]

ACS Chem Biol, 2023
McAvoy AC, Threatt PH, Kapcia J, Garg N.
europepmc   +1 more source

Identification and application of herbicide‐resistant 4‐hydroxyphenylpyruvate dioxygenase (HPPD) alleles via directed evolution

Plant Biotechnology Journal, Volume 23, Issue 10, Page 4336-4338, October 2025.
Bingbing Zhao, Yao Wang, Miaoyi Zhou, Xinxiang Liu, Hanshuai Li, Zi Shi, Yuhui Guo, Ting Li, Fengling Yang, Ronghuan Wang, Jiuran Zhao, Ya Liu   +11 more
wiley   +1 more source

Smoothened-antagonists reverse homogentisic acid-induced alterations of Hedgehog signaling and primary cilium length in alkaptonuria [PDF]

, 2017
Alkaptonuria (AKU) is an ultra-rare genetic disease, in which the accumulation of a toxic metabolite, homogentisic acid (HGA) leads to the systemic development of ochronotic aggregates.
Maurizio Taddei, PETRICCI, ELENA, MANETTI, FABRIZIO, Elena Petricci, Orlandini, M, Thompson, Clare L., Bernardini, G, Taddei, M, Braconi, D, Santucci, A, Manetti, F, Daniela Braconi, Fabrizio Manetti, Giulia Bernardini, Geminiani, M, Knight, MM, Knight, Martin M., MILLUCCI, LIA, Thompson, CL, Stephen D. Thorpe, Thorpe, SD, GAMBASSI, SILVIA, Lia Millucci, Martin M. Knight, Petricci, E, Clare L. Thompson, Silvia Gambassi, Thorpe, Stephen D., BERNARDINI, GIULIA, BRACONI, DANIELA, Annalisa Santucci, SANTUCCI, ANNALISA, GEMINIANI, MICHELA, Millucci, L, TADDEI, MAURIZIO, Michela Geminiani, Maurizio Orlandini, Gambassi, S, ORLANDINI, MAURIZIO   +38 more
core   +1 more source

No silver lining with health misinformation: argyria caused by intentional silver consumption

Medical Journal of Australia, Volume 223, Issue 2, Page 68-70, July 2025.
Luke Collins, Logesh Palanikumar, Stephen Bacchi   +2 more
wiley   +1 more source

Cytotoxic activity of strawberry tree (Arbutus unedo L.) honey, its extract, and homogentisic acid on CAL 27, HepG2, and Caco-2 cell lines. [PDF]

Arh Hig Rada Toksikol, 2022
Jurič A, Huđek Turković A, Brčić Karačonji I, Prđun S, Bubalo D, Durgo K.   +5 more
europepmc   +1 more source