Results 71 to 80 of about 3,728 (176)

Cytotoxicity of Active Ingredients Extracted from Plants of the Brazilian “Cerrado”

Natural Product Communications, 2011
Cytotoxicity assays are needed for the screening of natural products with potential anti-inflammatory. The purpose of this study was to compare the basal cytotoxicity of active ingredients extracted from plants of the Brazilian “cerrado”.
Veronica CG Soares, Cibele Bonacorsi, Alana LB Andrela, Lígia V Bortoloti, Stepheny C de Campos, Fábio HR Fagundes, Márcio Piovani, Camila A Cotrim, Wagner Vilegas, Marcos H Toyama   +9 more
doaj   +1 more source

Clinically probable alkaptonuria-associated ochronosis presenting as multilevel cervical disc herniation with myeloradiculopathy managed by three-level C4–7 anterior cervical discectomy and fusion: a case report

Frontiers in Endocrinology
Background/introductionAlkaptonuria (AKU) is a rare disorder of tyrosine metabolism characterized by homogentisic acid accumulation and ochronotic pigment deposition in connective tissues.
Zichuan Wu, Zichuan Wu, Baifeng Sun, Junzhe Sheng, Yong Hu, Yong Hu, Yang Liu   +6 more
doaj   +1 more source

Arthroplasty for the treatment of joint degeneration caused by ochronosis in two cases

Acta Orthopaedica et Traumatologica Turcica, 2020
Ochronosis is a rare metabolic disease caused by the deficiency of the homogentisic acid oxidase enzyme. With increasing age, accumulation of pigment deposits of homogentisic acid in the joint cartilage results in ochronotic osteoarthritis.
Mehmet Kefeli, Yilmaz Tomak, Bilge Can, Sancar Baris   +3 more
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Assessment of mass spectrometric indicators of organic acids metabolism in children with sarcopenia on the background of protein-energy insufficiency. Pilot study

Acta Biomedica Scientifica
Introduction. The geriatric problem of sarcopenia is relevant for both therapists and pediatricians. Secondary sarcopenia is diagnosed at any age in severe diseases, as well as muscle loss and muscle strength due to protein-energy malnutrition (PEM) or ...
V. P. Novikova, A. N. Zavyalova, M. N. Yakovleva, E. L. Strukov, I. V. Kukes, T. D. Lunegov   +5 more
doaj   +1 more source

Primer reporte de alcaptonuria en el Perú

Revista Peruana de Medicina Experimental y Salud Pública
La alcaptonuria es un error innato del metabolismo causado por la deficiencia de la homogentisiato 1,2 dioxidasa (HGD), produciéndose un exceso de ácido homogentísico (HGA).
Daniel Guillén-Mendoza, María Quiroga de Michelena   +1 more
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CHEMICAL PREPARATION OF HOMOGENTISIC ACID

Journal of Biological Chemistry, 1949
L D, ABBOTT, J D, SMITH
openaire   +2 more sources

Biochemical Properties and Physiological Roles of Tyrosine Aminotransferases in Olive (Olea europaea L.)

Horticulturae
Increasing the tocopherol content in plant-derived foods not only improves their nutritional quality but may also enhance plant resilience against abiotic stress factors.
Jesús Expósito, Pilar Luaces, Rosario Sánchez, Paula Benabal, Carlos Sanz, Ana Gracia Pérez   +5 more
doaj   +1 more source

Extensive Dysregulation of Phenylalanine Metabolism Is Associated With Stress Hyperphenylalaninemia and 30‐Day Death in Critically Ill Patients With Acute Decompensated Heart Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Stress hyperphenylalaninemia predicts elevated mortality rates in patients with acute decompensated heart failure (ADHF). This study investigated the metabolic pathways underlying this association and identified a unique metabolic phenotype ...
Wei‐Siang Chen, Min‐Hui Liu, Yi‐Liang Tsou, Huang‐Ping Wu, Hsuan‐Ching Lin, Chung‐Yu Liang, Chao‐Hung Wang   +6 more
doaj   +1 more source

Ochronosis ,The Rare Cause of Chronic Low Back Pain: Report of A Case

Iranian Journal of Neurosurgery, 2019
Background and Importance: Alkaptonuria is a rare genetic disorder due to deficiency of the enzyme homogentisic acid Oxidase which results in the accumulation of homogentisic acid in various body tissues; it produces a multisystemic disorder with a ...
Ali Baradaran Bagheri, Farsad Biglari, Somayeh Soroureddin, Salman Azarsina, Mohammad Kamangar   +4 more
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A Previously Undiagnosed Case of Alkaptonuria: A Case Report

The Turkish Journal of Gastroenterology, 2013
Alkaptonuria is a rare metabolic disorder in the phenylalanine and tyrosine catabolic pathway which is characterized by the excessive excretion of homogentisic acid in the urine, ochronosis, and debilitating arthritis of the spine and large joints ...
Mohammed ALSBOU, Nesrin MWAFI
doaj