Results 11 to 20 of about 372,766 (340)

Consecutive functions of small GTPases guide HOPS-mediated tethering of late endosomes and lysosomes

Cell Reports, 2023
Summary: The transfer of endocytosed cargoes to lysosomes (LYSs) requires HOPS, a multiprotein complex that tethers late endosomes (LEs) to LYSs before fusion. Many proteins interact with HOPS on LEs/LYSs.
Ariane Schleinitz, Lara-Alina Pöttgen, Tal Keren-Kaplan, Jing Pu, Paul Saftig, Juan S. Bonifacino, Albert Haas, Andreas Jeschke   +7 more
doaj   +2 more sources

Vps8 overexpression inhibits HOPS-dependent trafficking routes by outcompeting Vps41/Lt

eLife, 2019
Two related multisubunit tethering complexes promote endolysosomal trafficking in all eukaryotes: Rab5-binding CORVET that was suggested to transform into Rab7-binding HOPS.
Péter Lőrincz, Lili Anna Kenéz, Sarolta Tóth, Viktória Kiss, Ágnes Varga, Tamás Csizmadia, Zsófia Simon-Vecsei, Gábor Juhász   +7 more
doaj   +2 more sources

Structure of the HOPS tethering complex, a lysosomal membrane fusion machinery

eLife, 2022
Lysosomes are essential for cellular recycling, nutrient signaling, autophagy, and pathogenic bacteria and viruses invasion. Lysosomal fusion is fundamental to cell survival and requires HOPS, a conserved heterohexameric tethering complex.
Dmitry Shvarev, Jannis Schoppe, Caroline König, A. Perz, Nadia Füllbrunn, S. Kiontke, Lars Langemeyer, D. Januliene, Kilian Schnelle, D. Kümmel, F. Fröhlich, A. Moeller, C. Ungermann   +12 more
semanticscholar   +1 more source

ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation

Developmental Cell, 2020
Autophagy acts as a cellular surveillance mechanism to combat invading pathogens. Viruses have evolved various strategies to block autophagy and even subvert it for their replication and release.
Guangyan Miao, Hongyu Zhao, Yan Li, Mingming Ji, Yong Chen, Yi Shi, Y. Bi, Peihui Wang, Hong Zhang   +8 more
semanticscholar   +1 more source

Bi-allelic variants in HOPS complex subunit VPS41 cause cerebellar ataxia and abnormal membrane trafficking

Brain : a journal of neurology, 2021
Membrane trafficking is a complex, essential process in eukaryotic cells responsible for protein transport and processing. Deficiencies in vacuolar protein sorting (VPS) proteins, key regulators of trafficking, cause abnormal intracellular segregation of
Leslie E. Sanderson, Kristina Lanko, M. Alsagob, Rawan Almass, N. AL-Ahmadi, M. Najafi, Mohammad A Al-Muhaizea, Hamad I. Alzaidan, H. Aldhalaan, Elena Perenthaler, H. C. van der Linde, A. Nikoncuk, Nikolas A. Kühn, D. Antony, T. Owaidah, S. Raskin, Luana Gabriela Dalla Rosa Vieira, R. Mombach, N. Ahangari, Tainá Regina Damaceno Silveira, N. Ameziane, A. Rolfs, Aljohara Alharbi, Raghda M Sabbagh, K. Alahmadi, Bashayer Alawam, H. Ghebeh, Aljouhra AlHargan, Anoud Albader, Faisal S Binhumaid, E. Goljan, D. Monies, Osama M. Mustafa, Mazhor Aldosary, Albandary Albakheet, B. Alyounes, Faten B Almutairi, A. Al-Odaib, D. Aksoy, A. Başak, R. Palvadeau, D. Trabzuni, J. Rosenfeld, E. G. Karimiani, B. Meyer, B. Karakas, F. Al-Mohanna, S. Arold, D. Çolak, R. Maroofian, H. Houlden, A. Bertoli-Avella, M. Schmidts, T. S. Barakat, T. V. van Ham, N. Kaya   +55 more
semanticscholar   +1 more source

Hops (Humulus lupulus L.) as a Novel Multipurpose Crop for the Mediterranean Region of Europe: Challenges and Opportunities of Their Cultivation

, 2021
The common hop (Humulus lupulus L.) is a dioecious perennial climbing plant, mainly known for the use of its female inflorescences (cones or, simply, “hops”) in the brewing industry.
F. Rossini, G. Virga, Paolo Loreti, N. Iacuzzi, R. Ruggeri, M. Provenzano   +5 more
semanticscholar   +1 more source

Characterization of Wild Corsican Hops and Assessment of the Performances of German Hops in Corsican Environmental Conditions through a Multidisciplinary Approach

Applied Sciences, 2021
Hops (Humulus lupulus L.) is a species that grows spontaneously in Corsica, but the characterization of this species in this territory has not yet been investigated.
A. Dabbous-Wach, M. Rodolfi, J. Paolini, Jean Costa, T. Ganino   +4 more
semanticscholar   +1 more source

Transmission Expansion Planning Model Considering Battery Energy Storage, TCSC and Lines Using AC OPF

IEEE Access, 2020
Flexibility has become a requirement for modern power systems dominated by renewable generation sources. It can be extracted from different assets, ranging from demand response to fast generating units.
Zora Luburic, Hrvoje Pandzic, Miguel Carrion   +2 more
doaj   +1 more source

Star Formation Under the Outflow: The Discovery of a Non-Thermal Jet from OMC-2 FIR 3 and its Relationship to the Deeply Embedded FIR 4 Protostar [PDF]

, 2017
We carried out multiwavelength (0.7-5 cm), multiepoch (1994-2015) Very Large Array (VLA) observations toward the region enclosing the bright far-IR sources FIR 3 (HOPS 370) and FIR 4 (HOPS 108) in OMC-2. We report the detection of 10 radio sources, seven
Anglada, Guillem, Carrasco-Gonzalez, Carlos, Diaz-Rodriguez, Ana K., Fischer, William J., Furlan, Elise, Gomez, Jose F., Gonzalez-Garcia, Beatriz, Loinard, Laurent, Manoj, P., Megeath, S. Thomas, Osorio, Mayra, Rodriguez, Luis F., Stanke, Thomas, Stutz, Amelia M., Tobin, John J., Vavrek, Roland, Watson, Dan M.   +16 more
core   +4 more sources

Mobile hop-by-hop multicast routing [PDF]

Computer Networks, 2004
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Rolland Vida, Luís Henrique Maciel Kosmalski Costa, Serge Fdida   +2 more
openaire   +2 more sources