Regulation of Host-Pathogen Interactions via the Ubiquitin System.
Annual Review of Microbiology, 2022 Ubiquitination is a posttranslational modification that regulates a multitude of cellular functions. Pathogens, such as bacteria and viruses, have evolved sophisticated mechanisms that evade or counteract ubiquitin-dependent host responses, or even ...
Rukmini Mukherjee, I. Dikič
semanticscholar +3 more sources
Peptidylarginine Deiminase Inhibition Abolishes the Production of Large Extracellular Vesicles From Giardia intestinalis, Affecting Host-Pathogen Interactions by Hindering Adhesion to Host Cells [PDF]
bioRxiv, 2019 Giardia intestinalis is an anaerobic protozoan that is an important etiologic agent of inflammation-driven diarrhea worldwide. Although self-limiting, a deep understanding of the factors involved in the pathogenicity that produces the disruption of the ...
Bruno Gavinho +8 more
semanticscholar +2 more sources
Battle royale: Immune response on biofilms - host-pathogen interactions.
Current Research in Immunology, 2023 The research interest of the scientific community in biofilm-forming microorganisms is growing due to the problems caused by their infections affecting humans and animals, mainly because of the difficulty of the host immune system in eradicating these ...
Sandra Pamela Cangui-Panchi +6 more
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Host–Pathogen Interactions Influencing Zoonotic Spillover Potential and Transmission in Humans
Viruses, 2023 Emerging infectious diseases of zoonotic origin are an ever-increasing public health risk and economic burden. The factors that determine if and when an animal virus is able to spill over into the human population with sufficient success to achieve ...
B. Escudero-Pérez +3 more
semanticscholar +1 more source
Editorial: Uropathogens, urinary tract infections, the host-pathogen interactions and treatment
Frontiers in Microbiology, 2023 COPYRIGHT © 2023 Behzadi, García-Perdomo, Autrán Gómez, Pinheiro and Sarshar. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
P. Behzadi +4 more
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In Vitro Models for Investigating Intestinal Host–Pathogen Interactions
Advancement of science, 2023 Infectious diseases are increasingly recognized as a major threat worldwide due to the rise of antimicrobial resistance and the emergence of novel pathogens. In vitro models that can adequately mimic in vivo gastrointestinal physiology are in high demand
Reece McCoy +7 more
semanticscholar +1 more source
Virulence factors of uropathogens and their role in host pathogen interactions
The Cell Surface, 2022 Gram-positive and Gram-negative bacterial pathogens are commonly found in Urinary Tract Infection (UTI), particularly infected in females like pregnant women, elder people, sexually active, or individuals prone to other risk factors for UTI.
Deenadayalan Karaiyagowder Govindarajan +1 more
semanticscholar +1 more source
Peptidylarginine Deiminase (PAD) and Post-Translational Protein Deimination—Novel Insights into Alveolata Metabolism, Epigenetic Regulation and Host–Pathogen Interactions [PDF]
, 2021 The alveolates (Superphylum Alveolata) comprise a group of primarily single-celled eukaryotes that have adopted extremely diverse modes of nutrition, such as predation, photoautotrophy and parasitism.
Lange, S. +5 more
core +1 more source
Nature Reviews Microbiology, 2020 Urinary tract infections (UTIs) are common, recurrent infections that can be mild to life-threatening. The continued emergence of antibiotic resistance, together with our increasing understanding of the detrimental effects conferred by broad-spectrum ...
R. Klein, S. Hultgren
semanticscholar +1 more source
Inside-out chicken enteroids with leukocyte component as a model to study host–pathogen interactions
Communications Biology, 2021 Mammalian three-dimensional (3D) enteroids mirror in vivo intestinal organisation and are powerful tools to investigate intestinal cell biology and host–pathogen interactions.
Tessa J. Nash +3 more
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