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PROTEOMICS, EarlyView.ABSTRACT Protein S‐palmitoylation, a reversible lipid modification, plays critical roles in regulating protein function and localization. However, its comprehensive role in the rapid reprogramming of macrophages during early immune responses remains incompletely understood.
Hyojung Kim +4 more
wiley +1 more source
Diversity of Avian Host defense peptide
The Journal of Animal Genetics, 2018 openaire +2 more sources
Developmental and Comparative Immunology, 2013 Host defense peptides (HDPs) are important effector molecules of the innate immune system of vertebrates. These antimicrobial peptides are also present in invertebrates, plants and fungi. HDPs display broad-spectrum antimicrobial activities and fulfill an important role in the first line of defense of many organisms.
Maarten Coorens +2 more
exaly +6 more sources
Host-defense peptides: from biology to therapeutic strategies
Cellular and Molecular Life Sciences, 2011 Primitive innate defense mechanisms in the form of gene-encoded antimicrobial peptides are now considered as potential candidates for the development of new therapeutics.
Maria Luisa Mangoni, Mangoni Maria Luisa
exaly +2 more sources
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Host defense peptides in burns
Burns, 2004Overuse of antibiotics and failure to apply basic infection control policies and procedures have contributed to the increasing multi-drug resistance of many nosocomial pathogens. The alarming increase of multi-drug-resistant bacteria (e.g. Pseudomonas aeruginosa, methicilin-resistant Staphylococci, vancomycin-resistant Enterococci) causes infected ...
L, Steinstraesser +3 more
openaire +2 more sources
International Journal of Molecular Sciences, 2009 Host defense peptides can modulate the innate immune response and boost infection-resolving immunity, while dampening potentially harmful pro-inflammatory (septic) responses.
Lars Steinstraesser +2 more
exaly +3 more sources
Antimicrobial Peptides: Amphibian Host Defense Peptides
Current Medicinal Chemistry, 2019Antimicrobial Peptides (AMPs) are one of the most common components of the innate immune system that protect multicellular organisms against microbial invasion. The vast majority of AMPs are isolated from the frog skin. Anuran (frogs and toads) skin contains abundant AMPs that can be developed therapeutically.
Jiri, Patocka +4 more
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Cationic host defense (antimicrobial) peptides
Current Opinion in Immunology, 2006Members of the cationic host defense (antimicrobial) peptide family are widely distributed in nature, existing in organisms from insects to plants to mammals and non-mammalian vertebrates. Although many demonstrate direct antimicrobial activity against bacteria, fungi, eukaryotic parasites and/or viruses, it has been established that cationic peptides ...
Kelly L, Brown, Robert E W, Hancock
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Host defense peptides and their antimicrobial-immunomodulatory duality
Immunobiology, 2011 Host defence peptides (HDPs) are short cationic molecules produced by the immune systems of most multicellular organisms and play a central role as effector molecules of innate immunity. Host defence peptides have a wide range of biological activities from direct killing of invading pathogens to modulation of immunity and other biological responses of ...
Lars Steinstraesser +2 more
exaly +3 more sources
Host Defense Peptides in the Oral Cavity
2008Publisher Summary Host defense peptides (HDPs) are important in defense of tissues throughout the human mouth. Like resident microbial populations, HDPs are diverse, species-specific, and site-specific, and they have evolved in response to selection pressures exerted by resident and pathogenic microbial populations.
Deirdre A, Devine, Celine, Cosseau
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