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Senescence and Host–Pathogen Interactions [PDF]
Cells, 2020 Damage to our genomes triggers cellular senescence characterised by stable cell cycle arrest and a pro-inflammatory secretome that prevents the unrestricted growth of cells with pathological potential. In this way, senescence can be considered a powerful innate defence against cancer and viral infection.
Daniel Humphreys +2 more
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The Allometry of Host-Pathogen Interactions [PDF]
PLoS ONE, 2007 Understanding the mechanisms that control rates of disease progression in humans and other species is an important area of research relevant to epidemiology and to translating studies in small laboratory animals to humans. Body size and metabolic rate influence a great number of biological rates and times.
Melanie E. Moses +2 more
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Phosphoinositides and host–pathogen interactions [PDF]
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2015 Phosphoinositides control key cellular processes including vesicular trafficking and actin polymerization. Intracellular bacterial pathogens manipulate phosphoinositide metabolism in order to promote their uptake by target cells and to direct in some cases the biogenesis of their replication compartments.
Andreas Kühbacher +6 more
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Host–Pathogen Interaction 3.0 [PDF]
International Journal of Molecular Sciences, 2022 Microorganisms can interact with plants, animals and humans in many different ways, e [...]
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Host-Pathogen Interactions of Retroviruses [PDF]
Molecular Biology International, 2012 Retroviruses, such as HIV-1, are enveloped RNA viruses that use the enzyme reverse transcriptase (RT) to make a DNA copy of their RNA genome during replication in the host cell. The retrovirus life cycle is generally divided into two distinct phases: the early and late phase.
Suryaram Gummuluru +5 more
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Arrestins in Host–Pathogen Interactions [PDF]
, 2013 In the context of host-pathogen interaction, host cell receptors and signaling pathways are essential for both invading pathogens, which exploit them for their own profit, and the defending organism, which activates early mechanism of defense, known as innate immunity, to block the aggression.
Stefano Marullo +2 more
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Host–pathogen interactions in bacterial meningitis [PDF]
Acta Neuropathologica, 2016 Bacterial meningitis is a devastating disease occurring worldwide with up to half of the survivors left with permanent neurological sequelae. Due to intrinsic properties of the meningeal pathogens and the host responses they induce, infection can cause relatively specific lesions and clinical syndromes that result from interference with the function of
Elaine Tuomanen +10 more
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Editorial: Tick-Host-Pathogen Interactions [PDF]
Frontiers in Cellular and Infection Microbiology, 2018 Editorial on the Research Topic.
Ard M. Nijhof +3 more
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Immunomodulation Induced by Host Pathogen Interaction [PDF]
Journal of Immunology Research, 2019 Controlling and preventing infections require deep understanding of the complex interplay that occurs between the host and pathogen following infection. In essence, immunomodulation is any process leading to an immune response that can be altered to a desired level.
Gheyath K. Nasrallah +6 more
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Actin dynamics in host–pathogen interaction [PDF]
FEBS Letters, 2018 The actin cytoskeleton and Rho GTPase signaling to actin assembly are prime targets of bacterial and viral pathogens, simply because actin is involved in all motile and membrane remodeling processes, such as phagocytosis, macropinocytosis, endocytosis, exocytosis, vesicular trafficking and membrane fusion events, motility, and last but not least ...
Stradal, Theresia E. B. +1 more
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